MEA Recording System Circuit Implementation

被引:0
|
作者
Fambrini, Francisco [1 ]
Saito, Jose Hiroki [1 ,2 ]
Del Val Cura, Luis Mariano [2 ]
机构
[1] Fed Univ Sao Carlos UFSCar, Sao Carlos, SP, Brazil
[2] Fac Campo Limpo Paulista FACCAMP, Grad Course Comp Sci, Campo Limpo Paulista, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
micro-electrode array; MEA; amplifier; filters; analog multiplexer; electrophysiological signal; AD converter;
D O I
暂无
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
This paper presents a Micro-Electrode Array (MEA) recording system with novel concept of a multiplexer coupled prior to the amplifier and filtering stages. It is described all the recording system, since the pre-amplifier, analog channel multiplexing, amplifier and filter, and AD conversion. For the AD conversion, it was used a commercial module called BeagleBoneBlack, which is an open source board, based on a 32-bit microprocessor, making it much easier to search for neuronal signals from the in-vitro culture on MEA. As result, it is presented the first one second recording data at 1 kHz frequency of Wistar rat embryo hippocampal neuron culture. One importance of such an in-vitro culture recording in human factor is in pharmacological drug tests, before its approval for medicinal use.
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页码:8515 / 8520
页数:6
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