MEA Recording System Circuit Implementation

被引：0

作者：

Fambrini, Francisco ^{[1
]}

Saito, Jose Hiroki ^{[1
,2
]}

Del Val Cura, Luis Mariano ^{[2
]}

机构：

[1] Fed Univ Sao Carlos UFSCar, Sao Carlos, SP, Brazil

[2] Fac Campo Limpo Paulista FACCAMP, Grad Course Comp Sci, Campo Limpo Paulista, SP, Brazil

来源：

IECON 2017 - 43RD ANNUAL CONFERENCE OF THE IEEE INDUSTRIAL ELECTRONICS SOCIETY | 2017年

基金：

巴西圣保罗研究基金会;

关键词：

micro-electrode array; MEA; amplifier; filters; analog multiplexer; electrophysiological signal; AD converter;

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This paper presents a Micro-Electrode Array (MEA) recording system with novel concept of a multiplexer coupled prior to the amplifier and filtering stages. It is described all the recording system, since the pre-amplifier, analog channel multiplexing, amplifier and filter, and AD conversion. For the AD conversion, it was used a commercial module called BeagleBoneBlack, which is an open source board, based on a 32-bit microprocessor, making it much easier to search for neuronal signals from the in-vitro culture on MEA. As result, it is presented the first one second recording data at 1 kHz frequency of Wistar rat embryo hippocampal neuron culture. One importance of such an in-vitro culture recording in human factor is in pharmacological drug tests, before its approval for medicinal use.

引用

页码：8515 / 8520

页数：6

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