Biocatalytic one-pot three-component synthesis of 4H-chromene derivatives in non-aqueous medium

被引：8

作者：

Shrivas, Prabhakar ^{[1
]}

Pratap, Umesh ^{[1
]}

机构：

[1] Visvesvaraya Natl Inst Technol, Dept Chem, Nagpur 440010, Maharashtra, India

来源：

CHEMICAL PAPERS | 2019年 / 73卷 / 05期

关键词：

Baker's yeast; Chromene; Knoevenagel condensation; Michael addition; Biocatalysis; BAKERS-YEAST; EFFICIENT SYNTHESIS; CATALYST; 2-AMINO-4H-CHROMENES; MALONONITRILE; CYCLIZATION; REDUCTION;

D O I：

10.1007/s11696-018-00679-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The baker's yeast catalyzed one-pot three-component cyclocondensation of salicylaldehyde, malononitrile or ethyl cyanoacetate, and nitroalkanes for the synthesis of substituted 2-amino-4H-chromene derivatives is presented. The highlights of the protocol is a use of a biodegradable catalyst which is inexpensive, having simple reaction conditions, in other words, at room temperature and neutral pH, good-to-excellent yield, and simple workup procedure. [GRAPHICS]

引用

页码：1301 / 1307

页数：7

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