Phenolic Constituents from the Stem Bark of Magnolia officinalis

被引：107
|
作者：
Shen, Chien-Chang [1 ]
Ni, Ching-Li [1 ]
Shen, Yuh-Chiang [1 ]
Huang, Yu-Ling [1 ]
Kuo, Ching-Hsia [1 ]
Wu, Tian-Shung [1 ]
Chen, Chien-Chih [1 ]
机构：
[1] Natl Res Inst Chinese Med, Taipei 112, Taiwan
来源：
JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 01期
关键词：
HONOKIOL;
D O I：
10.1021/np800494e
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new compounds, magnolianone (1), erythro-honokitriol (2), and threo-honokitriol (3), together with 14 known compounds, magnaldehyde (4), magnatriol B (5), randaiol (6), obovatol (7), magnolignan B (8a and 8b), magnolol, honokiol (9), p-hydroxylbenzaldehyde, coniferaldehyde, coniferol alcohol, syringaldehyde, syringaresinol, and acteoside, were isolated from the MeOH-soluble part of a water extract of the stem bark of Magnolia officinalis. Among these compounds, 2-8b were studied for anti-inflammatory and antioxidative activities. Compound 7 displayed more potent antioxidative potential than 9. Compounds 4-7 effectively inhibited LPS-induced NO production, whereas 5 and 6 were more potent than 9.
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页码：168 / 171
页数：4
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