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- [21] AT13148, an orally bioavailable AKT kinase inhibitor with potent anti-tumor activity in both in vitro and in vivo models exhibiting AKT pathway deregulationMOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3512S - 3512SLyons, John F.论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandGrimshaw, Kyla M.论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandWoodhead, Steven J.论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandFeltell, Ruth E.论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandReule, Matthias论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandSmyth, Tomko论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandSeavers, Lisa C.论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandHarada, Isobelle论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandHiggins, Jacqueline论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandSmith, Donna M.论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandFazal, Lynsey论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, EnglandWorkman, Paul论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sutton, Surrey, England Astex Therapeut Ltd, Cambridge, EnglandCollins, Ian论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sutton, Surrey, England Astex Therapeut Ltd, Cambridge, EnglandGarrett, Michelle D.论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sutton, Surrey, England Astex Therapeut Ltd, Cambridge, EnglandThompson, Neil T.论文数: 0 引用数: 0 h-index: 0机构: Astex Therapeut Ltd, Cambridge, England Astex Therapeut Ltd, Cambridge, England
- [22] Discovery of INCB9471, a Potent, Selective, and Orally Bioavailable CCR5 Antagonist with Potent Anti-HIV-1 ActivityACS MEDICINAL CHEMISTRY LETTERS, 2010, 1 (09): : 483 - 487Xue, Chu-Biao论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAChen, Lihua论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USACao, Ganfeng论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAZhang, Ke论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAWang, Anlai论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAMeloni, David论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAGlenn, Joseph论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAAnand, Rajan论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAXia, Michael论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAKong, Ling论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAHuang, Taisheng论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAFeng, Hao论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAZheng, Changsheng论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USALi, Mei论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAGalya, Laurine论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAZhou, Jiacheng论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAShin, Niu论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USABaribaud, Fredric论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USASolomon, Kim论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAScherle, Peggy论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAZhao, Bitao论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USADiamond, Sharon论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAEmm, Tom论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAKeller, Douglas论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAContel, Nancy论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAYeleswaram, Swamy论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAVaddi, Kris论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAHollis, Gregory论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USANewton, Robert论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAFriedman, Steven论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USAMetcalf, Brian论文数: 0 引用数: 0 h-index: 0机构: Incyte Corp, Wilmington, DE 19880 USA Incyte Corp, Wilmington, DE 19880 USA
- [23] Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway ScreenJOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (04) : 1717 - 1735Mallinger, Aurelie论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandCrumpler, Simon论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandPichowicz, Mark论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandWaalboer, Dennis论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandStubbs, Mark论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandAdeniji-Popoola, Olajumoke论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandWood, Bozena论文数: 0 引用数: 0 h-index: 0机构: Cardiff Univ, Sch Biosci, Cardiff CF10 3XQ, S Glam, Wales Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandSmith, Elizabeth论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandThai, Ching论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandHenley, Alan T.论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandGeorgi, Katrin论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandCourt, William论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandHobbs, Steve论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandBox, Gary论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandOrtiz-Ruiz, Maria-Jesus论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandValenti, Melanie论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandBrandon, Alexis De Haven论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandTePoele, Robert论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandLeuthner, Birgitta论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandWorkman, Paul论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandAherne, Wynne论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandPoeschke, Oliver论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandDale, Trevor论文数: 0 引用数: 0 h-index: 0机构: Cardiff Univ, Sch Biosci, Cardiff CF10 3XQ, S Glam, Wales Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandWienke, Dirk论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandEsdar, Christina论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandRohdich, Felix论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandRaynaud, Florence论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandClarke, Paul A.论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandEccles, Suzanne A.论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandStieber, Frank论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandSchiemann, Kai论文数: 0 引用数: 0 h-index: 0机构: Merck Serono, Merck KGaA, D-64293 Darmstadt, Germany Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, EnglandBlagg, Julian论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SW7 3RP, England
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