Electrical Impedance Spectroscopy for Characterization of Prostate PC-3 and DU 145 Cancer Cells

被引：0
|
作者：
Teixeira, Viviane S. [1 ]
Barth, Tobias [1 ]
Labitzky, Vera [2 ]
Schumacher, Udo [2 ]
Krautschneider, Wolfgang [1 ]
机构：
[1] Hamburg Univ Technol, Inst Integrated Circuits, Hamburg, Germany
[2] Univ Med Ctr Hamburg Eppendorf UKE, Inst Anat & Expt Morphol, Ctr Expt Med, Hamburg, Germany
来源：
2019 41ST ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2019年
关键词：
D O I：
10.1109/embc.2019.8856627
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The impedance profile of the human PC-3 and DU 145 prostate cancer cells were recorded and compared using Electrical Impedance Spectroscopy. Cells were measured in a special chamber using a four terminal setup to avoid parasitic effects of electrode polarization in low frequencies. Our results show that the two cancer cell lines are readily distinguishable by their impedance spectrum. As PC-3 cells have been shown to be spontaneously metastatic in previous xenograft experiments while DU 145 cells were non-metastatic, Electrical Impedance Spectroscopy has the potential to be developed into a simple diagnostic tool to distinguish metastatic from non-metastatic cells.
引用
收藏
页码：6485 / 6489
页数：5
相关论文
共 50 条
  • [41] Calcilytics inhibit the proliferation and migration of human prostate cancer PC-3 cells
    Yamamura, Aya
    Nayeem, Md Junayed
    Sato, Motohiko
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2019, 139 (03) : 254 - 257
  • [42] Effect of prostatic neuropeptides on invasion and migration of PC-3 prostate cancer cells
    Nagakawa, O
    Ogasawara, M
    Fujii, H
    Murakami, K
    Murata, J
    Fuse, H
    Saiki, I
    CANCER LETTERS, 1998, 133 (01) : 27 - 33
  • [43] Eicosanoids regulation of transcription factors in PC-3 prostate cancer cells.
    Kandouz, M
    Honn, KV
    EICOSANOIDS AND OTHER BIOACTIVE LIPIDS IN CANCER, INFLAMMATION, AND RADIATION INJURY, 5, 2002, 507 : 563 - 568
  • [44] The Biological Effect of Hepsin on the Proliferation and Invasion of PC-3 Prostate Cancer Cells
    Yong Xu Zhiqiang Fan Jantao Sun Ranlu Liu Weiming Zhao Chunyu Wang Jo Zhang Tianjin Institute of Urology
    Chinese Journal of Clinical Oncology, 2006, (04) : 288 - 291
  • [45] Ouabain induces two modes of apoptosis in prostate cancer PC-3 cells
    Guh, J. H.
    Huang, Y. T.
    Huang, D. M.
    Teng, C. M.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2001, 15 : 147 - 147
  • [46] Cholesterol regulates prostasome release in human prostate cancer PC-3 cells
    Llorente, A.
    van Deurs, B.
    Sandvig, K.
    FEBS JOURNAL, 2007, 274 : 110 - 110
  • [47] Expression of nucleostemin in prostate cancer and its effect on the proliferation of PC-3 cells
    Liu Ran-Lu
    Zhang Zhi-Hong
    Zhao Wei-Ming
    Wang Meng
    Qi Shi-Yong
    Li Jing
    Zhang Yue
    Li Sheng-Zhi
    Xu Yong
    CHINESE MEDICAL JOURNAL, 2008, 121 (04) : 299 - 304
  • [48] SHARPIN overexpression induces tumorigenesis in human prostate cancer LNCaP, DU145 and PC-3 cells via NF-κB/ERK/Akt signaling pathway
    Jin Li
    Yiming Lai
    Yi Cao
    Tao Du
    Lexiang Zeng
    Ganping Wang
    Xianju Chen
    Jieqing Chen
    Yongsheng Yu
    Simin Zhang
    Yiming Zhang
    Hai Huang
    Zhenghui Guo
    Medical Oncology, 2015, 32
  • [49] RADIOBIOLOGICAL STUDIES OF PC-3 AND DU-145 HUMAN PROSTATE-CANCER CELLS - X-RAY-SENSITIVITY INVITRO AND HYPOXIC FRACTIONS OF XENOGRAFTED TUMORS INVIVO
    LEITH, JT
    QUARANTO, L
    PADFIELD, G
    MICHELSON, S
    HERCBERGS, A
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1993, 25 (02): : 283 - 287
  • [50] SHARPIN overexpression induces tumorigenesis in human prostate cancer LNCaP, DU145 and PC-3 cells via NF-κB/ERK/Akt signaling pathway
    Li, Jin
    Lai, Yiming
    Cao, Yi
    Du, Tao
    Zeng, Lexiang
    Wang, Ganping
    Chen, Xianju
    Chen, Jieqing
    Yu, Yongsheng
    Zhang, Simin
    Zhang, Yiming
    Huang, Hai
    Guo, Zhenghui
    MEDICAL ONCOLOGY, 2015, 32 (02)
12345