Quantitative phase contrast optimised cancerous cell differentiation via ptychography

被引：27
|
作者：
Claus, Daniel [1 ]
Maiden, Andrew M. [1 ]
Zhang, Fucai [1 ]
Sweeney, Francis G. R. [1 ]
Humphry, Martin J. [2 ]
Schluesener, Hermann [3 ]
Rodenburg, John M. [1 ]
机构：
[1] Univ Sheffield, Kroto Res Inst, Sheffield S3 7HQ, S Yorkshire, England
[2] Phase Focus Ltd, Sheffield S3 7HQ, S Yorkshire, England
[3] Univ Tubingen, Div Immunopathol Nervous Syst, D-72076 Tubingen, Germany
来源：
OPTICS EXPRESS | 2012年 / 20卷 / 09期
基金：
英国工程与自然科学研究理事会;
关键词：
DIFFRACTION;
D O I：
10.1364/OE.20.009911
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
This paper shows that visible-light ptychography can be used to distinguish quantitatively between healthy and tumorous unstained cells. Advantages of ptychography in comparison to conventional phase-sensitive imaging techniques are highlighted. A novel procedure to automatically refocus ptychographic reconstructions is also presented, which improves quantitative analysis. (C) 2012 Optical Society of America
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收藏
页数：8
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