Optimization of rivastigmine nanoemulsion for enhanced brain delivery: in-vivo and toxicity evaluation

被引:35
|
作者
Haider, Md. Faheem [1 ]
Khan, Saba [1 ]
Gaba, Bharti [1 ]
Alam, Tausif [1 ]
Baboota, Sanjula [1 ]
Ali, Javed [1 ]
Ali, Asgar [1 ]
机构
[1] Jamia Hamdard, Sch Pharmaceut Educ & Res, Dept Pharmaceut, New Delhi 110062, India
关键词
NANOSTRUCTURED LIPID CARRIERS; BOX-BEHNKEN; PHARMACOKINETIC EVALUATION; FORMULATION DEVELOPMENT; CHITOSAN NANOPARTICLES; INTRANASAL DELIVERY; ALZHEIMERS-DISEASE; DESIGN; DRUG; SYSTEM;
D O I
10.1016/j.molliq.2018.01.123
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:384 / 396
页数:13
相关论文
共 50 条
  • [1] Development of cannabidiol nanoemulsion for direct nose to brain delivery: statistical optimization, in vitro and in vivo evaluation
    Ahmed, Bakr
    Rizwanullah, Md
    Mir, Showkat Rasool
    Akhtar, M. Shaheer
    Amin, Saima
    [J]. BIOMEDICAL MATERIALS, 2022, 17 (06)
  • [2] ApoE3 Anchored Liposomal Delivery of Rivastigmine for Brain Delivery: Formulation, Characterization, and In Vivo Pharmacokinetic Evaluation
    Pooja Khairnar
    Ajit Singh
    Kailash Ahirwar
    Rahul Shukla
    [J]. AAPS PharmSciTech, 24
  • [3] ApoE3 Anchored Liposomal Delivery of Rivastigmine for Brain Delivery: Formulation, Characterization, and In Vivo Pharmacokinetic Evaluation
    Khairnar, Pooja
    Singh, Ajit
    Ahirwar, Kailash
    Shukla, Rahul
    [J]. AAPS PHARMSCITECH, 2023, 24 (08)
  • [4] Enhanced transdermal delivery of lutein via nanoethosomal gel: Formulation optimization, in-vitro evaluation, and in-vivo assessment
    Nikhat, Andleeb
    Hasan, Nazeer
    Iqbal, Zeenat
    Kesharwani, Prashant
    Talegaonkar, Sushama
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2022, 73
  • [5] Characterisation, in-vitro and in-vivo evaluation of valproic acid-loaded nanoemulsion for improved brain bioavailability
    Tan, Suk Fei
    Kirby, Brian P.
    Stanslas, Johnson
    Bin Basri, Hamidon
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2017, 69 (11) : 1447 - 1457
  • [6] In vitro and in vivo evaluation of indomethacin nanoemulsion as a transdermal delivery system
    El-Leithy, Eman S.
    Ibrahim, Howida Kamal
    Sorour, Rania M.
    [J]. DRUG DELIVERY, 2015, 22 (08): : 1010 - 1017
  • [7] IN-VIVO GENE-TRANSFER INTO INJURED CAROTID ARTERIES - OPTIMIZATION AND EVALUATION OF ACUTE TOXICITY
    SCHULICK, AH
    NEWMAN, KD
    VIRMANI, R
    DICHEK, DA
    [J]. CIRCULATION, 1995, 91 (09) : 2407 - 2414
  • [8] Formulation and In-vivo Pharmacokinetic Consideration of Intranasal Microemulsion and Mucoadhesive Microemulsion of Rivastigmine for Brain Targeting
    Brijesh Shah
    Dignesh Khunt
    Manju Misra
    Harish Padh
    [J]. Pharmaceutical Research, 2018, 35
  • [9] Formulation of Niosomal Gel for Enhanced Transdermal Lornoxicam Delivery: In-Vitro and In-Vivo Evaluation
    El-Ridy, Mohamed Shafik
    Yehia, Soad Aly
    Mohsen, Amira Mohamed
    El-Awdan, Sally A.
    Darwish, Asmaa Badawy
    [J]. CURRENT DRUG DELIVERY, 2018, 15 (01) : 122 - 133
  • [10] EVALUATION OF A NOVEL COLONIC DELIVERY DEVICE IN-VIVO
    QUADROS, E
    CASSIDY, J
    HIRSCHBERG, Y
    OBERLE, R
    CARR, J
    SAVASTANO, L
    [J]. STP PHARMA SCIENCES, 1995, 5 (01): : 77 - 82