In order to solve the problem of early differential diagnosis of ovarian cancer, this paper proposes the role of bioinformatics analysis in early differential diagnosis of ovarian cancer. This method uses bioinformatics methods to mine the existing data in the tumor database and obtain tumor-related molecules. It is an efficient method to obtain effective biomarkers, screen signal pathway molecules, and reveal the internal mechanism of tumor occurrence and development. Using this method can greatly improve the efficiency and reliability of screening diagnosis, prognosis, and treatment targets. The results showed that 5821 new lncRNA transcripts and 4611 new lncRNA genes were identified by lncScore from the assembled transcripts. 10 new lncRNA transcripts and 174 new lncRNA genes were found to be differentially expressed in ovarian cancer.
机构:
Amman Arab Univ, Fac Comp Sci & Informat, Amman, JordanAmman Arab Univ, Fac Comp Sci & Informat, Amman, Jordan
Alazzam, Malik Bader
AlGhamdi, Ahmed S.
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Taif Univ, Dept Comp Engn, Coll Comp & Informat Technol, POB 11099, At Taif 21944, Saudi ArabiaAmman Arab Univ, Fac Comp Sci & Informat, Amman, Jordan
AlGhamdi, Ahmed S.
Alshamrani, Sultan S.
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Taif Univ, Coll Comp & Informat Technol, Dept Informat Technol, POB 11099, At Taif 21944, Saudi ArabiaAmman Arab Univ, Fac Comp Sci & Informat, Amman, Jordan
机构:
Shengjing Hosp China Med Univ, Dept Obstet & Gynaecol, Shenyang 110004, Peoples R ChinaShengjing Hosp China Med Univ, Dept Obstet & Gynaecol, Shenyang 110004, Peoples R China
Fu, Ling-jie
Wang, Bing
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Shengjing Hosp China Med Univ, Dept Ultrasound, Shenyang 110004, Peoples R ChinaShengjing Hosp China Med Univ, Dept Obstet & Gynaecol, Shenyang 110004, Peoples R China
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Second Hosp Jilin Univ, Dept Neurosurg, Changchun, Peoples R China
Jilin Univ, China Japan Union Hosp, Dept Neurosurg, Changchun, Peoples R ChinaSecond Hosp Jilin Univ, Dept Neurosurg, Changchun, Peoples R China
Huang, Zhehao
Wang, Hailiang
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Second Hosp Jilin Univ, Dept Neurosurg, Changchun, Peoples R ChinaSecond Hosp Jilin Univ, Dept Neurosurg, Changchun, Peoples R China
Wang, Hailiang
Sun, Dongjie
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Jilin Univ, Coll Basic Med Sci, Changchun, Peoples R ChinaSecond Hosp Jilin Univ, Dept Neurosurg, Changchun, Peoples R China
Sun, Dongjie
Liu, Jun
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Second Hosp Jilin Univ, Dept Neurosurg, Changchun, Peoples R ChinaSecond Hosp Jilin Univ, Dept Neurosurg, Changchun, Peoples R China