Microcalorimetric study of Staphylococcus aureus growth affected by selenium compounds

被引：20
|
作者：
Li, X
Liu, Y [1 ]
Wu, J
Liang, HG
Qu, SS
机构：
[1] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China
[2] Wuhan Univ Technol, Sch Mat Sci & Technol, Wuhan 430070, Peoples R China
[3] Wuhan Univ, Dept Chem, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China
来源：
THERMOCHIMICA ACTA | 2002年 / 387卷 / 01期
关键词：
selenium compound; Staphylococcus aureus; inhibition; microcalorimetry; thermokinetics;
D O I：
暂无
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
The effect of four kinds of the selenium compounds on Staphylococcus aureus growth was studied by microcalorimetry. The extent and duration of the inhibitory effect on the metabolism as judged from the rate constant (k), varied with the different drugs. The rate constant of S. aureus (in log phase) in the presence of the drugs decreased with increasing concentrations of the drugs. The experimental results reveal that the sequence of antibiotic activity of selenomorpholines is: N,N'-methylene bisselenomorpholine > selenomorpholine and Na2SeO3 > selenomorpholine hydrochloride. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：57 / 61
页数：5
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