Neoadjuvant Treatment With Cyclooxygenase-2 Inhibitor and Prednisolone Allows Conservative Surgery for Inflammatory Myofibroblastic Tumor of the Bladder

被引:12
|
作者
Tsuma, Yusuke [1 ]
Miyachi, Mitsuru [1 ]
Ouchi, Kazutaka [1 ]
Tsuchiya, Kunihiko [1 ]
Iehara, Tomoko [1 ]
Naitoh, Yasuyuki [2 ]
Konishi, Eiichi [3 ]
Yanagisawa, Akio [3 ]
Hosoi, Hajime [1 ]
机构
[1] Kyoto Prefectural Univ Med, Dept Pediat, Kyoto, Japan
[2] Kyoto Prefectural Univ Med, Dept Urol, Grad Sch Med Sci, Kyoto, Japan
[3] Kyoto Prefectural Univ Med, Dept Pathol, Kyoto, Japan
关键词
inflammatory myofibroblastic tumor; cyclooxygenase-2; neoadjuvant treatment; PLASMA-CELL GRANULOMA; THERAPY; LUNG;
D O I
10.1097/MPH.0000000000000604
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Inflammatory myofibroblastic tumor (IMT), which expresses cyclooxygenase-2 (COX-2), can be effectively treated with COX-2 inhibitor. Here, we report a case of urinary bladder IMT in a 13-year-old boy. Although total cystectomy was initially planned for complete resection of the tumor, neoadjuvant treatment with COX-2 inhibitor and prednisolone reduced the size of the tumor and enabled complete resection of the tumor by partial cystectomy. Neoadjuvant treatment with COX-2 inhibitor and prednisolone for IMT of the bladder allowed a more conservative surgical procedure that preserved bladder function.
引用
收藏
页码:E283 / E285
页数:3
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