Targeting Glutathione Reductase in KEAP1/NRF2 Mutant NSCLC

被引:0
|
作者
Jiang, Chang [1 ]
DeNicola, Gina [2 ]
机构
[1] H Lee Moffitt Canc Ctr & Res Inst, Canc Physiol, Tampa, FL USA
[2] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
关键词
D O I
10.1016/j.freeradbiomed.2022.10.186
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
179
引用
收藏
页数:2
相关论文
共 50 条
  • [41] MicroRNA-200a improves diabetic endothelial dysfunction by targeting KEAP1/NRF2
    Jiang, Ziping
    Wu, Junduo
    Ma, Fuzhe
    Jiang, Jun
    Xu, Linlin
    Du, Lei
    Huang, Wenlin
    Wang, Zhaohui
    Jia, Ye
    Lu, Laijin
    Wu, Hao
    JOURNAL OF ENDOCRINOLOGY, 2020, 245 (01) : 129 - 140
  • [42] Pterostilbene-mediated Nrf2 activation: Mechanistic insights on Keap1:Nrf2 interface
    Bhakkiyalakshmi, Elango
    Dineshkumar, Kesavan
    Karthik, Suresh
    Sireesh, Dornadula
    Hopper, Waheeta
    Paulmurugan, Ramasamy
    Ramkumar, Kunka Mohanram
    BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 24 (16) : 3378 - 3386
  • [43] KEAP1/NRF2 (NFE2L2) mutations in NSCLC-Fuel for a superresistant phenotype?
    Dempke, Wolfram C. M.
    Reck, Martin
    LUNG CANCER, 2021, 159 : 10 - 17
  • [44] The Role of the Keap1/Nrf2 Pathway in the Cellular Response to Methylmercury
    Kumagai, Yoshito
    Kanda, Hironori
    Shinkai, Yasuhiro
    Toyama, Takashi
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2013, 2013
  • [45] The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism
    Song, Moon-Young
    Lee, Da-Young
    Chun, Kyung-Soo
    Kim, Eun-Hee
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (09)
  • [46] Nrf2/Keap1/ARE信号通路与眼科疾病
    赵玉霞
    姚进
    眼科新进展, 2014, 34 (11) : 1097 - 1100
  • [47] Discovery of the Negative Regulator of Nrf2, Keap1: A Historical Overview
    Itoh, Ken
    Mimura, Junsei
    Yamamoto, Masayuki
    ANTIOXIDANTS & REDOX SIGNALING, 2010, 13 (11) : 1665 - 1678
  • [48] Succinylation of a KEAP1 sensor lysine promotes NRF2 activation
    Ibrahim, Lara
    Stanton, Caroline
    Nutsch, Kayla
    Nguyen, Thu
    Li-Ma, Chloris
    Ko, Yeonjin
    Lander, Gabriel C.
    Wiseman, R. Luke
    Bollong, Michael J.
    CELL CHEMICAL BIOLOGY, 2023, 30 (10) : 1295 - +
  • [49] The role of the Nrf2/Keap1 pathway in obesity and metabolic syndrome
    Zhang, Zhiguo
    Zhou, Shanshan
    Jiang, Xin
    Wang, Yue-Hui
    Li, Fengsheng
    Wang, Yong-Gang
    Zheng, Yang
    Cai, Lu
    REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2015, 16 (01): : 35 - 45
  • [50] The Role of NRF2/KEAP1 Pathway in Glioblastoma: Pharmacological Implications
    Shahcheraghi, Seyed Hossein
    Salemi, Fateme
    Alam, Waqas
    Ashworth, Henry
    Saso, Luciano
    Khan, Haroon
    Lotfi, Marzieh
    MEDICAL ONCOLOGY, 2022, 39 (05)