Frequency analysis of the CCR5Δ32 mutation in patients with brucellosis

被引：7
|
作者：
Skendros, P
Boura, P
Tsantas, N
Debre, P
Theodorou, I
机构：
[1] Aristotle Univ Thessaloniki, Hippokrat Hosp, Dept Internal Med 2, Clin Immunol Lab, Thessaloniki 54642, Greece
[2] Aristotle Univ Thessaloniki, Dept Math, Sect Stat Probabil & OR, GR-54006 Thessaloniki, Greece
[3] Hop La Pitie Salpetriere, INSERM, UR543, Lab Cent Immunol Cellulaire & Tissulaire, Paris, France
来源：
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 2002年 / 34卷 / 12期
关键词：
D O I：
10.1080/0036554021000026975
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
This study investigated the influence of the host's CCR5 genotype in human brucellosis. Genotype analysis for the CCR5Delta32 mutation was performed in 185 brucellosis patients and 141 healthy volunteers, all recruited in northern Greece. In the brucellosis-infected patients the CCR5Delta32 genotype distribution showed a significant deviation from the Hardy-Weinberg equilibrium ( p = 0.030), owing to the presence of 2 individuals homozygous for Delta32 among the 185 brucellosis patients compared with none of the 141 controls. Extended studies should be performed to confirm an association between CCR5 genotype and the risk of acquiring brucellosis.
引用
收藏
页码：944 / 946
页数：3
相关论文
共 50 条
  • [1] The frequency of CCR5 promoter polymorphisms and CCR5 Δ 32 mutation in Iranian populations
    Zare-Bidaki, Mohammad
    Karimi-Googheri, Masoud
    Hassanshahi, Gholamhossein
    Zainodini, Nahid
    Arababadi, Mohammad Kazemi
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2015, 18 (04) : 312 - 316
  • [2] ASSOCIATION OF CCR5Δ32 MUTATION IN BREAST CANCER PATIENTS OF PAKISTAN
    Fatima, Faria
    Hameed, Abdul
    Sultan, Naheed
    Azhar, Abid
    Saleem, Saima
    Asia-Pacific Journal of Clinical Oncology, 2015, 11 : 171 - 171
  • [3] Frequency of CCR5Δ32 in Brazilian populations
    Vargas, AE
    Marrero, AR
    Salzano, FM
    Bortolini, MC
    Chies, JAB
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2006, 39 (03) : 321 - 325
  • [4] Low frequency of the ccr5Δ32 HIV-resistance allele in mainland China:: Identification of the first case of ccr5Δ32 mutation in the Chinese population
    Jiang, JD
    Wang, Y
    Wang, ZZ
    Chen, XH
    Guo, ZM
    Pan, HL
    Bekesi, GJ
    Wang, AX
    Chen, HS
    SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 1999, 31 (04) : 345 - 348
  • [5] THE FREQUENCY OF ALLELE CCR5Δ32 IN A SERBIAN POPULATION
    Dordevic, Valentina
    Timotijevic, Gordana
    Pruner, Iva
    Radojkovic, Dragica
    Milovanovic, Bosko
    Miljkovic, Dorde
    JOURNAL OF MEDICAL BIOCHEMISTRY, 2013, 32 (04) : 368 - 374
  • [6] Frequency of the CCR5Δ32 allele in the Moroccan population
    Elharti, E
    Elaouad, R
    Simons, MJ
    Messouak-Elhachimi, Z
    Gluckman, JC
    Parmentier, M
    Benjouad, A
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2000, 16 (01) : 87 - 89
  • [7] No association between asthma or allergy and the CCR5Δ 32 mutation
    Nagy, A
    Kozma, GT
    Bojszkó, A
    Krikovszky, D
    Falus, A
    Szalai, C
    ARCHIVES OF DISEASE IN CHILDHOOD, 2002, 86 (06) : 426 - 427
  • [8] CCR5Δ32 mutation, Mycoplasma pneumoniae infection, and asthma
    Ungvavi, Ildiko
    Tolgyesi, Gergely
    Semsei, Agnes F.
    Nagy, Adrienne
    Radosits, Karoly
    Keszei, Marton
    Kozma, Gergely T.
    Falus, Andras
    Szalai, Csaba
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (06) : 1545 - 1547
  • [9] The frequency of mutation in CCR5 gene among Koreans
    Oh, MD
    Kim, SS
    Kim, EY
    Kim, N
    Park, KY
    Kim, U
    Kim, T
    Kim, T
    Choe, K
    Lee, JS
    INTERNATIONAL JOURNAL OF STD & AIDS, 2000, 11 (04) : 266 - 267
  • [10] No association of CCR5Δ32 gene mutation with multiple sclerosis in Croatian and Slovenian patients
    Ristic, S
    Lovrecic, L
    Starcevic-Cizmarevic, N
    Brajenovic-Milic, B
    Jazbec, SS
    Barac-Latas, V
    Vejnovic, D
    Sepcic, J
    Kapovic, M
    Peterlin, B
    MULTIPLE SCLEROSIS, 2006, 12 (03): : 360 - 362
12345