Two New ent-Labdane Diterpenes from the Roots of Euphorbia yinshanica

被引：3

作者：

Zhang, Ben-Yin ^{[1
,2
]}

Yin, Heng-Xia ^{[1
]}

Zhang, De-Jun ^{[1
,2
]}

机构：

[1] Qinghai Univ, State Key Lab Plateau Ecol & Agr, Xining 810008, Peoples R China

[2] Qinghai Univ, Coll Ecoenvironm Engn, Xining 810008, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2017年 / 53卷 / 02期

基金：

中国国家自然科学基金;

关键词：

PLATYCLADUS-ORIENTALIS; CONSTITUENTS;

D O I：

10.1007/s10600-017-1973-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new ent-labdane diterpenes, ent-3 alpha,16-dihydroxylabda-8(17),12(E),14-triene (1) and ent-14(S),15-dihydroxylabda-8(17)-12(E)-dien-18-oic acid (2), were isolated from the roots of Euphorbia yinshanica. Their structures were elucidated on the basis of spectroscopic methods including HR-ESI-MS and 1D and 2D NMR. The cytotoxic activities against five tumor cell lines was also evaluated, but there was no significant activity.

引用

页码：295 / 298

页数：4

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