Isolated lung perfusion for pulmonary metastases, a review and work in progress

被引:18
|
作者
Grootenboers, Marco J. J. H.
Heeren, Jos
van Putte, Bart P.
Hendriks, Jeroen M. H.
van Boven, Wim J.
Van Schil, Paul E. Y.
Schramel, Franz M. N. H.
机构
[1] St Antonius Hosp, Dept Pulm Med, NL-3430 EM Nieuwegein, Netherlands
[2] St Antonius Hosp, Dept Anesthesiol, NL-3430 EM Nieuwegein, Netherlands
[3] St Antonius Hosp, Dept Cardiothorac Surg, NL-3430 EM Nieuwegein, Netherlands
[4] Univ Antwerp Hosp, Dept Thorac & Vasc Surg, Edegem, Belgium
来源
PERFUSION-UK | 2006年 / 21卷 / 05期
关键词
D O I
10.1177/0267659106073984
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pulmonary metastasectomy is a widely accepted treatment for many patients with pulmonary metastases from various solid tumors. Nevertheless, 5-year survival is disappointing, with rates of 25-40%, and many patients develop recurrences. Isolated lung perfusion (ILuP) is a promising new technique to deliver high-dose chemotherapy to the lungs, while minimising systemic toxicities. This procedure is technically safe and feasible; however, clinical value and efficacy remain unclear. The aim of this paper is to give a review of literature on ILuP in humans, and to describe the development of the perfusion procedure in our institute.
引用
收藏
页码:267 / 276
页数:10
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