Catalyst-free three-component synthesis of 2-amino-4,6-diarylpyridine-3-carbonitriles under solvent-free conditions

被引：5
|
作者：
Sayahi, Mohammad Hosein [1 ]
Saghanezhad, Seyyed Jafar [2 ]
Mandavi, Mohammad [3 ]
机构：
[1] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran
[2] ACECR Prod Technol Res Inst, POB 61396-84689, Ahvaz, Iran
[3] Univ Tehran Med Sci, Endocrinol & Metab Clin Sci Inst, Endocrinol & Metab Res Ctr, POB 14117-13137, Tehran, Iran
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2019年 / 55卷 / 08期
关键词：
acetophenone oximes; 2-amino-4,6-diarylpyridine-3-carbonitriles; solvent-free synthesis; ONE-POT SYNTHESIS; 2-AMINO-3-CYANOPYRIDINE DERIVATIVES; EFFICIENT; INHIBITORS; DISCOVERY;
D O I：
10.1007/s10593-019-02527-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel efficient one-pot synthesis of 2-amino-4,6-diarylpyridine-3-carbonitriles is described. Method involves heating the mixture of an acetophenone oxime, aldehyde, and malononitrile without any catalyst under solvent-free conditions to give the title compounds in good to high yields.
引用
收藏
页码：725 / 728
页数：4
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