Interfacing carbon nanotubes with living cells

被引:235
|
作者
Chen, Xing
Tam, Un Chong
Czlapinski, Jennifer L.
Lee, Goo Soo
Rabuka, David
Zettl, Alex [1 ]
Bertozzi, Carolyn R.
机构
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA
[3] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
[4] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA
[5] Lawrence Berkeley Lab, Div Sci Mat, Berkeley, CA 94720 USA
关键词
D O I
10.1021/ja060276s
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We developed a polymer coating for carbon nanotubes (CNTs) that mimics the mucin glycoprotein coating of mammalian cells. CNTs coated with these mucin mimic polymers have two novel properties: they can bind to carbohydrate receptors, providing a means for biomimetic interactions with cell surfaces, and, importantly, they are rendered nontoxic to cells. Copyright © 2006 American Chemical Society.
引用
收藏
页码:6292 / 6293
页数:2
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