Relationship Between Cyclophilin A Levels and Matrix Metalloproteinase 9 Activity in Cerebrospinal Fluid of Cognitively Normal Apolipoprotein E4 Carriers and Blood-Brain Barrier Breakdown

被引：97

作者：

Halliday, Matthew R. ^{[1
,2
]}

Pomara, Nunzio ^{[3
]}

Sagare, Abhay P. ^{[2
]}

Mack, Wendy J. ^{[4
]}

Frangione, Blas ^{[3
]}

Zlokovic, Berislav V. ^{[2
]}

机构：

[1] Univ So Calif, Neurosci Grad Program, Los Angeles, CA 90089 USA

[2] Univ So Calif, Keck Sch Med, Zilkha Neurogenet Inst, Dept Physiol & Biophys,Ctr Neurodegenerat & Regen, Los Angeles, CA 90089 USA

[3] NYU, Sch Med, Dept Psychiat, Nathan S Kline Inst Psychiat Res, Orangeburg, NY USA

[4] Univ So Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90089 USA

来源：

JAMA NEUROLOGY | 2013年 / 70卷 / 09期

关键词：

ALZHEIMERS-DISEASE; DISORDERS;

D O I：

10.1001/jamaneurol.2013.3841

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

[No abstract available]

引用

页码：1198 / 1200

页数：3

共 28 条

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[22] Potential Contribution of Hypoxia-Inducible Factor-1α, Aquaporin-4, and Matrix Metalloproteinase-9 to Blood-Brain Barrier Disruption and Brain Edema After Experimental Subarachnoid Hemorrhage
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[23] The Inclusion of a Matrix Metalloproteinase-9 Responsive Sequence in Self-assembled Peptide-based Brain-Targeting Nanoparticles Improves the Efficiency of Nanoparticles Crossing the Blood-Brain Barrier at Elevated MMP-9 Levels
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[24] BI 409306, A Novel PDE9 Inhibitor, Crosses the Blood-Brain Barrier and Triggers Dose- and Concentration-Dependent Increases in Cerebrospinal Fluid (CSF) Cyclic Guanosine Monophosphate (cGMP) Levels
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[25] Performance on a pattern separation task by Alzheimer’s patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels
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[26] Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels
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[27] RELATIONSHIP BETWEEN CIRCULATING LEVELS OF FOLLICULE STIMULATING (FSH), LUTEINIZING (LH), GROWTH (GH) HORMONES AND PROLACTIN (PRL) IN BLOOD AND IN CEREBROSPINAL-FLUID (CSF) - EVIDENCE FOR A DIRECT PASSAGE OF PRL THROUGH THE BLOOD-BRAIN-BARRIER
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[28] Exendin-4 Preserves Blood-Brain Barrier Integrity via Glucagon-Like Peptide 1 Receptor/Activated Protein Kinase-Dependent Nuclear Factor-Kappa B/Matrix Metalloproteinase-9 Inhibition After Subarachnoid Hemorrhage in Rat
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