Electrical detection of femtomolar DNA via gold-nanoparticle enhancement in carbon-nanotube-network field-effect transistors

被引：91

作者：

Dong, Xiaochen ^{[1
,2
]}

Lau, Ching Man ^{[1
]}

Lohani, Anup ^{[1
]}

Mhaisalkar, Subodh G. ^{[1
]}

Kasim, Johnson ^{[3
]}

Shen, Zexiang ^{[3
]}

Ho, Xinning ^{[4
]}

Rogers, John A. ^{[4
]}

Li, Lain-Jong ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 637819, Singapore

[2] Nanjing Univ Posts & Telecommun, Inst Adv Mat, Nanjing 210046, Peoples R China

[3] Nanyang Technol Univ, Sch Phys & Math Sci, Singapore 637371, Singapore

[4] Univ Illinois, Dept Chem, Dept Mat Sci & Engn, Urbana, IL 61801 USA

来源：

ADVANCED MATERIALS | 2008年 / 20卷 / 12期

关键词：

D O I：

10.1002/adma.200702798

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A dramatic sensitivity enhancement in electrical detection of DNA hybridization using single-walled carbon nanotube networked field effect transistors (SNFETs) via introducing reporter DNA-Au nanoparticle (AuNP) conjugates in the hybridization step is reported. The amplified change in drain current allows to reliably determine the DNA concentration down to similar to 100 fM.

引用

页码：2389 / +

页数：6

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