A kinetic model for actinorhodin production by Streptomyces coelicolor A3(2)

被引:32
|
作者
Elibol, M [1 ]
Mavituna, F
机构
[1] Firat Univ, Dept Chem Engn, TR-23279 Elazig, Turkey
[2] Univ Manchester, Inst Sci & Technol, Dept Chem Engn, Manchester M60 1QD, Lancs, England
关键词
actinorhodin; Streptomyces coelicolor; kinetic model; logistic equation; Luedeking-Piret equations;
D O I
10.1016/S0032-9592(98)00136-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The fermentation kinetics of an extracellular antibiotic, actinorhodin, by Streptomyces coelicolor were studied in a batch system. A simple model was proposed using the Logistic equation for growth, the Luedeking-Piret equation for actinorhodin production and Luedeking-Piret-like equations for glucose and oxygen consumptions. The model appeared to provide a reasonable description for each parameter during the growth phase. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:625 / 631
页数:7
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