Formal synthesis of (±)-cladoniamide G

被引：13
|
作者：
Ngernmeesri, Paiboon [1 ]
Soonkit, Sarochar
Konkhum, Anothai
Kongkathip, Boonsong
机构：
[1] Kasetsart Univ, Fac Sci, Dept Chem, Bangkok 10900, Thailand
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 09期
关键词：
Natural product synthesis; Anticancer; (+/-)-Cladoniamide G; Suzuki-Miyaura coupling; BENZANNULATION REACTIONS; STAUROSPORINE AGLYCON; BIOLOGICAL-ACTIVITIES; ENT-STAUROSPORINE; PARTIAL AGONISTS; CALOTHRIXIN-B; REBECCAMYCIN; INDOLOCARBAZOLES; (+)-STAUROSPORINE; DERIVATIVES;
D O I：
10.1016/j.tetlet.2014.01.086
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The formal synthesis of (+/-)-cladoniamide G, a natural product that exhibits cytotoxicity against human breast cancer MCF-7 cells, is presented. Our strategy employed a Suzuki-Miyaura coupling to join the two indole subunits of this natural product. (c) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1621 / 1624
页数：4
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