Formal synthesis of (±)-cladoniamide G

被引：13

作者：

Ngernmeesri, Paiboon ^{[1
]}

Soonkit, Sarochar

Konkhum, Anothai

Kongkathip, Boonsong

机构：

[1] Kasetsart Univ, Fac Sci, Dept Chem, Bangkok 10900, Thailand

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 09期

关键词：

Natural product synthesis; Anticancer; (+/-)-Cladoniamide G; Suzuki-Miyaura coupling; BENZANNULATION REACTIONS; STAUROSPORINE AGLYCON; BIOLOGICAL-ACTIVITIES; ENT-STAUROSPORINE; PARTIAL AGONISTS; CALOTHRIXIN-B; REBECCAMYCIN; INDOLOCARBAZOLES; (+)-STAUROSPORINE; DERIVATIVES;

D O I：

10.1016/j.tetlet.2014.01.086

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The formal synthesis of (+/-)-cladoniamide G, a natural product that exhibits cytotoxicity against human breast cancer MCF-7 cells, is presented. Our strategy employed a Suzuki-Miyaura coupling to join the two indole subunits of this natural product. (c) 2014 Elsevier Ltd. All rights reserved.

引用

页码：1621 / 1624

页数：4

共 50 条

[1] Total Synthesis of Cladoniamide G
Loosley, Benjamin C.
Andersen, Raymond J.
Dake, Gregory R.
ORGANIC LETTERS, 2013, 15 (05) : 1152 - 1154
[2] Unsymmetrical vic-Tricarbonyl Compounds for the Total Syntheses of Cladoniamide G and Cladoniamide F
Schuette, Julia
Kilgenstein, Frank
Fischer, Michel
Koert, Ulrich
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2014, 2014 (24) : 5302 - 5311
[3] Total synthesis of gonytolides C and G, lachnone C, and formal synthesis of blennolide C and diversonol
Sudhakar, Gangarajula
Bayya, Shruthi
Kadam, Vilas D.
Nanubolu, Jagadeesh Babu
ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12 (30) : 5601 - 5610
[4] Xenocladoniamide F, minimal indolotryptoline from the cladoniamide pathway
Du, Yi-Ling
Ding, Tong
Patrick, Brian O.
Ryan, Katherine S.
TETRAHEDRON LETTERS, 2013, 54 (41) : 5635 - 5638
[5] A Formal Synthesis of Betamethasone
Wang, Shasha
Shi, Yong
Tian, Weisheng
CHINESE JOURNAL OF CHEMISTRY, 2015, 33 (06) : 637 - 642
[6] Formal synthesis of Pellasoren - A
Muralikrishna, Katta
Kumar, Gavireddy Chaithanya
Satyanarayana, Vavilapalli
Kumar, R. Sudheer
Yadav, Jhillu Singh
TETRAHEDRON LETTERS, 2018, 59 (48) : 4209 - 4212
[7] Formal synthesis of epibatidine
Chang, MY
Chen, HP
HETEROCYCLES, 2005, 65 (07) : 1705 - 1711
[8] FORMAL SYNTHESIS OF ISOCOMENE
LEE, HW
LEE, JH
LEE, IYC
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 1991, 12 (04) : 392 - 397
[9] A FORMAL SYNTHESIS OF STEGANONE
AIDHEN, IS
NARASIMHAN, NS
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1993, 32 (02): : 211 - 221
[10] A FORMAL SYNTHESIS OF BRUCEANTIN
SASAKI, M
MURAE, T
TETRAHEDRON LETTERS, 1989, 30 (03) : 355 - 356

← 1 2 3 4 5 →