Nucleoside analogues exerting antiviral activity through a non-nucleoside mechanism

被引：18
|
作者：
De Clercq, E [1 ]
机构：
[1] Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium
来源：
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2004年 / 23卷 / 1-2期
关键词：
neucloside analogues; HCMV; HIV;
D O I：
10.1081/NCN-120028339
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In analogy with maribavir [1-(beta-L-ribofuranosyl)-isopropylamino-5,6-dichlorobenzimidazole], a nucleoside analogue that acts against human cytomegalovirus (HCMV) by a non-nucleoside mechanism, here I present three other examples of classes of nucleoside analogues (i.e. bicyclic furo[2,3-d]pyrimidine as well as HEPT and TSAO derivatives) that act against either HCMV or human immunodeficiency virus (HIV) through a non-nucleoside mode of action.
引用
收藏
页码：457 / 470
页数：14
相关论文
共 50 条
  • [1] Antifungal activity of nucleoside analogues and non-nucleoside reverse transcriptase inhibitors
    Mata-Essayag, S
    Magaldi, S
    Hartung, C
    Calatroni, MI
    Perez, C
    Colella, MT
    Olaizola, C
    Rosello, A
    Henao, L
    [J]. JOURNAL DE MYCOLOGIE MEDICALE, 2004, 14 (03): : 123 - 128
  • [2] Anti-HSV nucleoside and non-nucleoside analogues: spectroscopic characterisation of naphthyl and coumarinyl amides and their mode and mechanism of antiviral action
    Das Mahapatra, Ananya
    Patra, Chiranjit
    Sepay, Nayim
    Sinha, Chittaranjan
    Chattopadhyay, Debprasad
    [J]. 3 BIOTECH, 2023, 13 (07)
  • [3] Anti-HSV nucleoside and non-nucleoside analogues: spectroscopic characterisation of naphthyl and coumarinyl amides and their mode and mechanism of antiviral action
    Ananya Das Mahapatra
    Chiranjit Patra
    Nayim Sepay
    Chittaranjan Sinha
    Debprasad Chattopadhyay
    [J]. 3 Biotech, 2023, 13
  • [4] Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents
    Franchetti, P
    Grifantini, M
    [J]. CURRENT MEDICINAL CHEMISTRY, 1999, 6 (07) : 599 - 614
  • [5] Review on fluorinated nucleoside/non-nucleoside FDA-approved antiviral drugs
    Ismail, Magda M. F.
    Ayoup, Mohammed Salah
    [J]. RSC ADVANCES, 2022, 12 (48) : 31032 - 31045
  • [6] Antiviral activity of nucleoside analogues against norovirus
    Costantini, Veronica P.
    Whitaker, Tony
    Barclay, Leslie
    Lee, David
    McBrayer, Tamara R.
    Schinazi, Raymond F.
    Vinje, Jan
    [J]. ANTIVIRAL THERAPY, 2012, 17 (06) : 981 - 991
  • [7] Antiviral activity of nucleoside analogues: The BVDU connection
    De Clercq, E
    [J]. RECENT ADVANCES IN NUCLEOSIDES: CHEMISTRY AND CHEMOTHERAPY, 2002, : 433 - 454
  • [8] Antiviral activity of new triazine nucleoside analogues
    Nosach, L
    Alexeeva, I
    Palchikovskaya, L
    Povnitsa, O
    Usenko, L
    Dyachenko, N
    [J]. ANTIVIRAL RESEARCH, 2004, 62 (02) : A74 - A74
  • [9] Fascinating Transformation of SAM-Competitive Protein Methyltransferase Inhibitors from Nucleoside Analogues to Non-Nucleoside Analogues
    Talukdar, Arindam
    Mukherjee, Ayan
    Bhattacharya, Debomita
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2022, 65 (03) : 1662 - 1684
  • [10] Advanced Prodrug Strategies in Nucleoside and Non-Nucleoside Antiviral Agents: A Review of the Recent Five Years
    Sinokrot, Hanadi
    Smerat, Tasneem
    Najjar, Anas
    Karaman, Rafik
    [J]. MOLECULES, 2017, 22 (10)
12345