Performance of Vitek 2 in antimicrobial susceptibility testing of Pseudomonas aeruginosa isolates with different mechanisms of β-lactam resistance

被引：10

作者：

Mazzariol, Annarita ^{[1
]}

Aldegheri, Marco ^{[1
]}

Ligozzi, Marco ^{[1
]}

Lo Cascio, Giuliana ^{[2
]}

Koncan, Raffaella ^{[1
]}

Fontana, Roberta ^{[1
]}

机构：

[1] Univ Verona, Clin Microbiol Lab, Dipartimento Patol, Sez Microbiol, I-37134 Verona, Italy

[2] Azienda Osped, Serv Microbiol Immunol & Virol, Verona, Italy

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 06期

关键词：

D O I：

10.1128/JCM.02216-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A total of 78 isolates of Pseudomonas aeruginosa grouped according to the phenotype for ceftazidime and imipenem susceptibility/resistance were used to assess the accuracy of the Vitek 2 system in antimicrobial susceptibility testing. Comparisons were made with a MIC gradient test for piperacillin-tazobactam, ceftazidime, aztreonam, imipenem, meropenem, gentamicin, and ciprofloxacin. For the total of 546 isolate-antimicrobial combinations tested, the category agreement was 83.6%, with 2.0, 1.6, and 12.8% very major, major, and minor errors, respectively. Vitek 2 accuracy was influenced differently by the mechanism responsible for resistance, and interpretation of the results in relation to phenotype could improve the performance of the system.

引用

页码：2095 / 2098

页数：4

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