Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C-H functionalization of alcohols

被引：179
|
作者：
Meng, Yuan
Guo, Li-Na [1 ]
Wang, Hua
Duan, Xin-Hua
机构：
[1] Xi An Jiao Tong Univ, Dept Chem, Sch Sci, Xian 710049, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 68期
基金：
中国国家自然科学基金;
关键词：
CATALYTIC ASYMMETRIC-SYNTHESIS; INTRAMOLECULAR HECK REACTIONS; QUATERNARY CARBON CENTERS; BOND FORMATION; COUPLING REACTION; OXINDOLES; RADICALS; ETHERS;
D O I：
10.1039/c3cc44055a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A metal-free tandem radical addition/cyclization reaction of activated alkenes and alcohols has been developed. The process provides an efficient and atom economical access to various valuable hydroxylcontaining oxindoles through the direct sp(3) C-H functionalization of alcohols.
引用
收藏
页码：7540 / 7542
页数：3
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