Personality profile of patients with juvenile myoclonic epilepsy

In the study described here we attempted to evaluate the personality profiles of 25 patients with juvenile myoclonic epilepsy UME) at the time of diagnosis, before treatment, and to explore a potential relationship between behavioral aspects and clinical outcome. For this purpose we employed a standardized and objective instrument, the Minnesota Multiphasic Personality Inventory (MMPI). and found that patients with JME have a personality profile similar to that of the control group, which corresponds to the 3,1 code type MMPI Profile. We also noted that the characteristics of this personality type include those described in patients with long-duration JME by previous researchers. Consequently, we conclude that personality aberrations are not a feature of this syndrome. Furthermore, we observed that under treatment, EEGs normalized in patients who had exhibited "psychotic tendencies" pretreatment. The credibility of our results is supported by the fact that assessment of the personality profile was not confounded by medication or the longitudinal burden of epileptic seizures. (C) 2008 Elsevier Inc. All rights reserved.