Beyond PARP-POLθ as an anticancer target

被引：59
|
作者：
Higgins, Geoff S. [1 ]
Boulton, Simon J. [2 ,3 ]
机构：
[1] Univ Oxford, Inst Radiat Oncol, Canc Res UK Med Res Council Oxford, Old Rd,Campus Res Bldg,Roosevelt Dr, Oxford OX3 7DQ, England
[2] Francis Crick Inst, 1 Midland Rd, London NW1 1AT, England
[3] Artios Pharma Ltd, Babraham Res Campus, Cambridge CB22 3AT, England
来源：
SCIENCE | 2018年 / 359卷 / 6381期
关键词：
POLYMERASE-THETA; REPAIR; RECOMBINATION; CANCER; OLAPARIB; THERAPY; TUMORS; TRIAL; CELLS; NHEJ;
D O I：
10.1126/science.aar5149
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：1217 / +
页数：2
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