Recent Progress Towards the Identification of Inhibitors of Mycobacterial Cell Wall Polysaccharide Biosynthesis

被引:46
|
作者
Lowary, Todd L. [1 ]
机构
[1] Ohio State Univ, Dept Chem, 100 West 18th Ave, Columbus, OH 43210 USA
基金
美国国家卫生研究院;
关键词
Tuberculsosis; mycobacteria; polysaccharides; furanosides; bacterial cell wall; inhibitors;
D O I
10.2174/1389557033487683
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Mycobacterial infections have recently attracted significant attention from international health agencies due to the resurgence of these diseases worldwide. This review summarizes the recent work directed towards the identification of new anti-tuberculosis agents that act by inhibiting mycobacterial cell wall polysaccharide biosynthesis.
引用
收藏
页码:689 / 702
页数:14
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