Recent Progress Towards the Identification of Inhibitors of Mycobacterial Cell Wall Polysaccharide Biosynthesis

被引:46
|
作者
Lowary, Todd L. [1 ]
机构
[1] Ohio State Univ, Dept Chem, 100 West 18th Ave, Columbus, OH 43210 USA
基金
美国国家卫生研究院;
关键词
Tuberculsosis; mycobacteria; polysaccharides; furanosides; bacterial cell wall; inhibitors;
D O I
10.2174/1389557033487683
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Mycobacterial infections have recently attracted significant attention from international health agencies due to the resurgence of these diseases worldwide. This review summarizes the recent work directed towards the identification of new anti-tuberculosis agents that act by inhibiting mycobacterial cell wall polysaccharide biosynthesis.
引用
收藏
页码:689 / 702
页数:14
相关论文
共 50 条
  • [1] Plant cell wall polysaccharide biosynthesis: real progress in the identification of participating genes
    Burton, RA
    Farrokhi, N
    Bacic, A
    Fincher, GB
    PLANTA, 2005, 221 (03) : 309 - 312
  • [2] Plant cell wall polysaccharide biosynthesis: real progress in the identification of participating genes
    Rachel A. Burton
    Naser Farrokhi
    Antony Bacic
    Geoffrey B. Fincher
    Planta, 2005, 221 : 309 - 312
  • [3] Recent advances in mycobacterial cell wall glycan biosynthesis
    Tam, Pui-Hang
    Lowary, Todd L.
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2009, 13 (5-6) : 618 - 625
  • [4] Analogues of the mycobacterial arabinogalactan linkage disaccharide as cell wall biosynthesis inhibitors
    Wen, XH
    Crick, DC
    Brennan, PJ
    Hultin, PG
    BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 11 (17) : 3579 - 3587
  • [5] Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall
    Mikusova, Katarina
    Belanova, Martina
    Kordulakova, Jana
    Honda, Kristine
    McNeil, Michael R.
    Mahapatra, Sebabrata
    Crick, Dean C.
    Brennan, Patrick J.
    JOURNAL OF BACTERIOLOGY, 2006, 188 (18) : 6592 - 6598
  • [6] Synthesis of Arabino glycosyl triazoles as potential inhibitors of mycobacterial cell wall biosynthesis
    Wilkinson, Brendan L.
    Long, Hilary
    Sim, Edith
    Fairbanks, Antony J.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (23) : 6265 - 6267
  • [7] Synthesis of arabinose glycosyl sulfamides as potential inhibitors of mycobacterial cell wall biosynthesis
    Suthagar, Kajitha
    Watson, Andrew J. A.
    Wilkinson, Brendan L.
    Fairbanks, Antony J.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 102 : 153 - 166
  • [8] RECENT PROGRESS IN INHIBITORS OF POLYAMINE BIOSYNTHESIS
    STANEK, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 133 - MEDI
  • [9] A new perspective on Mycobacterial cell wall biosynthesis and the identification of potential drug targets
    Alderwick, Luke J.
    Seidel, Mathias
    Eggeling, Lothar
    Besra, Gurdyal S.
    GLYCOBIOLOGY, 2006, 16 (11) : 1144 - 1144
  • [10] Bacterial cell wall polysaccharide biosynthesis
    Kiessling, Laura L.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245