The lung fibroblast as "soil fertilizer'' in breast cancer metastasis

被引：3
|
作者：
Houthuijzen, Julia M. [1 ]
de Visser, Karin E. [2 ,3 ]
机构：
[1] Netherlands Canc Inst, Div Mol Pathol, Oncode Inst, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands
[2] Netherlands Canc Inst, Div Tumor Biol & Immunol, Oncode Inst, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands
[3] Leiden Univ, Dept Immunol, Med Ctr, Leiden, Netherlands
来源：
IMMUNITY | 2022年 / 55卷 / 08期
基金：
荷兰研究理事会;
关键词：
D O I：
10.1016/j.immuni.2022.07.010
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Fibroblasts strongly impact tumor progression, but whether they prime the pre-metastatic niche is poorly understood. In this issue of Immunity, Gong and Li et al. identify lung-specific immunosuppressive fibroblasts, which are hijacked by breast cancer cells to facilitate metastasis.
引用
收藏
页码：1336 / 1339
页数：5
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