Sensitization of resistant tumor cells for chemotherapy- or death-receptor-induced, apoptosis by restoration of absent caspase-8 expression through demethylation or caspase-8 gene transfer.

被引:0
|
作者
Fulda, S
Dockhorn-Dworniczak, B
Debatin, K
机构
[1] Univ Ulm, Childrens Hosp, Ulm, Germany
[2] Univ Munster, D-4400 Munster, Germany
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
273
引用
收藏
页码:3707S / 3708S
页数:2
相关论文
共 50 条
  • [41] Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment
    M Orzáez
    T Guevara
    M Sancho
    E Pérez-Payá
    Cell Death & Disease, 2012, 3 : e415 - e415
  • [42] Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth
    Li, Changyou
    Egloff, Ann Marie
    Sen, Malabika
    Grandis, Jennifer R.
    Johnson, Daniel E.
    MOLECULAR ONCOLOGY, 2014, 8 (07) : 1220 - 1230
  • [43] Staphylococcus aureus Induces Apoptosis in Primary Bovine Mammary Epithelial Cells Through Fas-FADD Death Receptor-Linked Caspase-8 Signaling
    Hu, Qingliang
    Cui, Xinjie
    Tao, Lin
    Xiu, Lei
    Wang, Ting
    Wang, Xiao
    DNA AND CELL BIOLOGY, 2014, 33 (06) : 388 - 397
  • [44] Histone deacetylase inhibitor-mediated sensitization to TRAIL-induced apoptosis in childhood malignancies is not associated with upregulation of TRAIL receptor expression, but with potentiated caspase-8 activation
    Sonnemann, Juergen
    Trommer, Navina
    Becker, Sabine
    Wittig, Susan
    Grauel, Desiree
    Palani, Chithra D.
    Beck, James F.
    CANCER BIOLOGY & THERAPY, 2012, 13 (06) : 417 - 424
  • [45] Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand
    Yasui, H
    Adachi, M
    Hamada, H
    Imai, K
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2005, 26 (02) : 537 - 544
  • [46] Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
    Harper, N
    Hughes, M
    MacFarlane, M
    Cohen, GM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (28) : 25534 - 25541
  • [47] Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction
    Yeo-Jin Chae
    Ho-Shik Kim
    Hyangshuk Rhim
    Bo-Eun Kim
    Seong-Whan Jeong
    In-Kyung Kim
    Experimental & Molecular Medicine, 2001, 33 : 284 - 292
  • [48] Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction
    Chae, YJ
    Kim, HS
    Rhim, H
    Kim, BE
    Jeong, SW
    Kim, IK
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2001, 33 (04): : 284 - 292
  • [49] Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: Role of caspase-8 and mitochondria
    Maya Ameyar-Zazoua
    Nathanaël Larochette
    Guillaume Dorothée
    Eric Daugas
    Hedi Haddada
    Vanessa Gouloumet
    Didier Métivier
    Rodica Stancou
    Fathia Mami-Chouaib
    Guido Kroemer
    Salem Chouaib
    Cancer Gene Therapy, 2002, 9 : 219 - 227
  • [50] Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells:: Role of caspase-8 and mitochondria
    Ameyar-Zazoua, M
    Larochette, N
    Dorothée, G
    Daugas, E
    Haddada, H
    Gouloumet, V
    Métivier, D
    Stancou, R
    Mami-Chouaib, F
    Kroemer, G
    Chouaib, S
    CANCER GENE THERAPY, 2002, 9 (03) : 219 - 227