Dual CCR2/CCR5 antagonism as macrophage targeted therapy in experimental hepatocellular carcinoma

被引：0

作者：

Degroote, Helena ^{[1
]}

Vandierendonck, Astrid ^{[2
]}

Xavier, Verhelst ^{[1
]}

Anja, Geerts ^{[1
]}

Hans, Van Vlierberghe ^{[1
]}

Devisscher, Lindsey ^{[2
]}

机构：

[1] Ghent Univ Hosp, Gastroenterol & Hepatol, Ghent, Belgium

[2] Univ Ghent, Basic & Appl Med Sci, Gut Liver Immunopharmacol Unit, Ghent, Belgium

来源：

JOURNAL OF HEPATOLOGY | 2019年 / 70卷 / 01期

关键词：

D O I：

10.1016/S0618-8278(19)30701-7

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

THU-454

引用

页码：E359 / E359

页数：1

共 50 条

[11] Elucidation of Binding Sites of Dual Antagonists in the Human Chemokine Receptors CCR2 and CCR5
Hall, Spencer E.
Mao, Allen
Nicolaidou, Vicky
Finelli, Mattea
Wise, Emma L.
Nedjai, Belinda
Kanjanapangka, Julie
Harirchian, Paymann
Chen, Deborah
Selchau, Victor
Ribeiro, Sofia
Schyler, Sabine
Pease, James E.
Horuk, Richard
Vaidehi, Nagarajan
MOLECULAR PHARMACOLOGY, 2009, 75 (06) : 1325 - 1336
[12] Improved Cognitive Performance and Reduced Monocyte Activation in Virally Suppressed Chronic HIV After Dual CCR2 and CCR5 Antagonism
D'Antoni, Michelle L.
Paul, Robert H.
Mitchell, Brooks I.
Kohorn, Lindsay
Fischer, Laurent
Lefebvre, Eric
Seyedkazemi, Star
Nakamoto, Beau K.
Walker, Maegen
Kallianpur, Kalpana J.
Ogata-Arakaki, Debra
Ndhlovu, Lishomwa C.
Shikuma, Cecilia
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2018, 79 (01) : 108 - 116
[13] Eotaxin: A CCR2 antagonist and a CCR5 agonist on human monocytes
Ogilvie, P
Bardi, G
Loetscher, P
Baggiolini, M
Uguccioni, M
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2000, 115 (03) : 532 - 532
[14] CCR2 and CCR5 gene polymorphisms and susceptibility to sarcoidosis.
Wischmeijer, TA
Bombieri, C
Agostini, C
Semenzato, GP
Luisetti, M
Pignatti, PF
AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (04) : 485 - 485
[15] CCR2 and CCR5 expression on monocytes during in vivo culture
Dagkalis, N
Xu, H
Mack, M
Liversidge, J
Crane, IJ
IMMUNOLOGY, 2005, 116 : 75 - 75
[16] Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice
Mack, M
Cihak, J
Simonis, C
Luckow, B
Proudfoot, AEI
Plachy, J
Brühl, H
Frink, M
Anders, HJ
Vielhauer, V
Pfirstinger, J
Stangassinger, M
Schlöndorff, D
JOURNAL OF IMMUNOLOGY, 2001, 166 (07): : 4697 - 4704
[17] CCR2/CCR5 antagonist cenicriviroc reduces colonic inflammation and fibrosis in experimental colitis
Song, Xin
Jiang, Chensheng
Yu, Mengli
Lu, Chao
He, Xinjue
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2024, 39 (08) : 1597 - 1605
[18] BMS-813160: A Potent CCR2 and CCR5 Dual Antagonist Selected as a Clinical Candidate
Cherney, Robert J.
Anjanappa, Prakash
Selvakumar, Kumaravel
Batt, Douglas G.
Brown, Gregory D.
Rose, Anne, V
Vuppugalla, Ragini
Chen, Jing
Pang, Jian
Xu, Songmei
Yarde, Melissa
Tebben, Andrew J.
Paidi, Venkatram Reddy
Cvijic, Mary Ellen
Mathur, Arvind
Barrish, Joel C.
Mandlekar, Sandhya
Zhao, Qihong
Carter, Percy H.
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 12 (11): : 1753 - 1758
[19] Discovery of a dual CCR2/CCR5 antagonist with a superior cardiovascular profile for the treatment of autoimmune diseases
Hughes, Robert O.
Rogier, D. Joseph
Devraj, Rajesh
Xue, Chu-Biao
Cao, Ganfeng
Turner, Steven R.
Morton, Philip A.
Keys, Kelly
Covington, Maryanne
Bond, Brian R.
Yu, Ying
Meade, Holly
Hood, William F.
Roeberds, Steve
Newton, Robert
Metcalf, Brian
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242
[20] Combination therapy with a dual CCR2/CCR5 antagonist and a FGF21 analogue synergizes in ameliorating steatohepatitis and fibrosis
Puengel, Tobias
Lefere, Sander
Hundertmark, Jana
Penners, Christian
Van de Velde, Frederique
Lapauw, Bruno
Devisscher, Lindsey
Geerts, Anja
Boehm, Stephanie
Zhao Qihong
Krupinski, John
Charles, Edgar
Zinker, Bradley
Tacke, Frank
JOURNAL OF HEPATOLOGY, 2020, 73 : S13 - S13

← 1 2 3 4 5 →