Polycyclic N-heterocyclic compounds.: 55.: A novel reaction of N-(5,6-dihydro[1]benzothiepino[5,4-d]pyrimidin-4-yl)amidine or its amide oxime derivatives with hydroxylamine

被引：7

作者：

Zhang, YX ^{[1
]}

Sasaki, K ^{[1
]}

Hirota, T ^{[1
]}

机构：

[1] Okayama Univ, Fac Pharmaceut Sci, Okayama 7008530, Japan

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1999年 / 36卷 / 03期

关键词：

D O I：

10.1002/jhet.5570360335

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of N-(5,6-dihydro[1]benzothiepino[5,4-d]pyrimidin-4-yl)amidines or its amide oxime derivatives with hydroxylamine hydrochloride under basic condition gave abnormal cyclization products via a ring cleavage of pyrimidine component accompanied with a ring closure of [1,2,4]oxadiazole.

引用

页码：787 / 791

页数：5

共 29 条

[21] Discovery of (+)-N-(3-Aminopropyl)-N-[1-(5-benzyl-3-metlyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-metlylpropyl]-4-methylbenzamide (AZD4877), a Kinesin Spindle Protein Inhibitor and Potential Anticancer Agent
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JOURNAL OF MEDICINAL CHEMISTRY, 2011, 54 (19) : 6734 - 6750
[22] POLYCYCLIC N-HETERO COMPOUNDS .39. A FACILE SYNTHESIS OF 1,2,4,5-TETRAHYDRO-[1]BENZOXEPINO[4,5-E]IMIDAZO[1,2-C]PYRIMIDINES VIA RING-CLOSURE OF 4-(2-HYDROXYALKYLAMINO)-5,6-DIHYDRO-[1]BENZOXEPINO[5,4-D]PYRIMIDINES
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[23] Polycyclic N-Heterocyclic Compounds. Part 79: Synthesis of 2,4-Disubstituted 6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidines as Potential Antiplatelet Aggregators
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JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 (06) : 1607 - 1614
[24] POLYCYCLIC N-HETEROCYCLIC COMPOUNDS .45. SYNTHESIS OF 4-SUBSTITUTED 5,6-DIHYDROBENZO[H]QUINAZOLINES AND 6,7-DIHYDRO-5H-BENZO[6,7]CYCLOHEPTA[1,2-D]PYRIMIDINES AND THEIR INHIBITORY ACTIVITY ON PLATELET-AGGREGATION
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JOURNAL OF HETEROCYCLIC CHEMISTRY, 1993, 30 (04) : 993 - 995
[25] Polycyclic N-heterocyclic compounds. Part 61: A novel Truce-Smiles type rearrangement reaction of 4-(2-cyanovinyloxy)butanenitriles to give cycloalkeno[1,2-d]furo[2,3-b]pyridines
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[26] Synthesis and Herbicidal Activity of Novel N-(2-Fluoro-5(3-methyl-2,6-dioxo-4-(trifluoromethyl)-2,3-dihydro-pyrimidin-1(6H)-yl)phenyl)-2-phenoxyacetamide Derivatives
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Mo Hongbo
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Ren Yeguo
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[27] POLYCYCLIC N-HETERO COMPOUNDS .21. SYNTHESIS OF NOVEL RING-SYSTEM, 4H-IMIDAZO[1',2'-1,6]PYRIMIDO[5,4-D][1]BENZAZEPINE AS "B-HOMO-6,11,13,15-TETRAAZASTEROIDAL ANALOG
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