MRP4 mediated transport is part of the physiological mechanism of elimination cyclic nucleotides from human platelets

被引:0
|
作者
Borgognone, A. [1 ]
Pulcinelli, F. M. [1 ]
机构
[1] Univ Roma La Sapienza, Dept Expt Med, Rome, Italy
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
O-TH-102
引用
收藏
页码:755 / 755
页数:1
相关论文
共 50 条
  • [31] CGMP and glutathione-conjugate transport in human erythrocytes - The roles of the multidrug resistance-associated proteins, MRP1, MRP4 and MRP5
    Klokouzas, A
    Wu, CP
    van Veen, HW
    Barrand, MA
    Hladky, SB
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 2003, 270 (18): : 3696 - 3708
  • [32] Aspirin influences MRP4 protein up-regulation in human platelets through a direct action on megakaryocytic gene expression
    Massimi, I.
    Guerriero, R.
    Lotti, L. V.
    Gaudio, C.
    Frati, L.
    Pulcinelli, F. M.
    EUROPEAN HEART JOURNAL, 2012, 33 : 603 - 603
  • [33] The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
    Jedlitschky, G
    Tirschmann, K
    Lubenow, LE
    Nieuwenhuis, HK
    Akkerman, JWN
    Greinacher, A
    Kroemer, HK
    BLOOD, 2004, 104 (12) : 3603 - 3610
  • [34] Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2-and MRP4/ABCC4-mediated methotrexate transport
    El-Sheikh, Azza A. K.
    van den Heuvel, Jeroen J. M. W.
    Koenderink, Jan B.
    Russel, Frans G. M.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2007, 320 (01): : 229 - 235
  • [35] ROLE OF CYCLIC-NUCLEOTIDES IN STORE-MEDIATED EXTERNAL CA2+ ENTRY IN HUMAN PLATELETS
    NAKAMURA, K
    KIMURA, M
    AVIV, A
    BIOCHEMICAL JOURNAL, 1995, 310 : 263 - 269
  • [36] TRANSPORT OF ENALAPRILAT, THE ACTIVE METABOLITE OF ENALAPRIL, ACROSS THE HEPATIC BASOLATERAL MEMBRANE IS MEDIATED BY MRP4 AND INHIBITED BY ROSUVASTATIN AND MK-571
    Ferslew, Brian
    Koeck, Kathleen
    Brouwer, Kim L. R.
    DRUG METABOLISM REVIEWS, 2012, 44 : 139 - 139
  • [37] Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport
    Jarvinen, Erkka
    Troberg, Johanna
    Kidron, Heidi
    Finel, Moshe
    MOLECULAR PHARMACEUTICS, 2017, 14 (10) : 3299 - 3311
  • [38] A Novel Pathway for Arsenic Elimination: Human Multidrug Resistance Protein 4 (MRP4/ABCC4) Mediates Cellular Export of Dimethylarsinic Acid (DMAV) and the Diglutathione Conjugate of Monomethylarsonous Acid (MMAIII)
    Banerjee, Mayukh
    Carew, Michael W.
    Roggenbeck, Barbara A.
    Whitlock, Brayden D.
    Naranmandura, Hua
    Le, X. Chris
    Leslie, Elaine M.
    MOLECULAR PHARMACOLOGY, 2014, 86 (02) : 168 - 179
  • [39] Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets
    Rosado, JA
    Porras, T
    Conde, M
    Sage, SO
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (19) : 15666 - 15675
  • [40] Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3-Overexpressing Human Embryonic Kidney 293 Cells
    Sun, Hua
    Wang, Xiao
    Zhou, Xiaotong
    Lu, Danyi
    Ma, Zhiguo
    Wu, Baojian
    DRUG METABOLISM AND DISPOSITION, 2015, 43 (10) : 1430 - 1440