The effect of the inhaled PDE4 inhibitor CHF6001 on allergen-induced inflammation in asthmatics

被引:0
|
作者
Singh, Dave
Leaker, Brian
Boyce, Malcom
Nandeuil, Marie -Anna
Collarini, Sara
Mariotti, Fabrizia
Santoro, Debora
Barnes, Peter J.
机构
关键词
Anti-inflammatory; COPD; -; management; Pharmacology;
D O I
暂无
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [41] CHF6001 Inhibits NF-κB Activation and Neutrophilic Recruitment in LPS-Induced Lung Inflammation in Mice
    Stellari, Fabio F.
    Sala, Angelo
    Ruscitti, Francesca
    Buccellati, Carola
    Allen, Andrew
    Rise, Patrizia
    Civelli, Maurizio
    Villetti, Gino
    FRONTIERS IN PHARMACOLOGY, 2019, 10
  • [42] New Inhaled Pan-Jak Inhibitor A Is Efficacious At Reducing Allergen-Induced Airway Inflammation In Rat
    Ramis, I.
    Calama, E.
    Domenech, A.
    Carreno, C.
    Calaf, E.
    Cordoba, M.
    Alberti, J.
    De Alba, J.
    Bach, J.
    Prats, N.
    Miralpeix, M.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
  • [43] Effects of inhaled budesonide on allergen-induced airway responses and airway inflammation
    Gauvreau, GM
    Doctor, J
    Watson, RM
    Jordana, M
    OByrne, PM
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1996, 154 (05) : 1267 - 1271
  • [44] Effects of fluticasone on allergen-induced asthmatic responses and airway inflammation in mild asthmatics.
    Dente, FL
    Scuotri, L
    Bartoli, ML
    Carnevali, S
    Clanchetti, S
    Bacci, E
    Di Franco, A
    Giannini, D
    Taccola, M
    Vagaggini, B
    Paggiaro, PL
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (03) : A634 - A634
  • [45] Reduction in systemic inflammation by the PDE4 inhibitor roflumilast in patients with COPD
    -Martin, Eduardo Marquez
    Ruiz, Francisco Ortega
    Campano, Elena
    De la Horra, Carmen
    Varela, Jose Manuel
    Calderon, Enrique
    EUROPEAN RESPIRATORY JOURNAL, 2014, 44
  • [46] Reduction in Systemic Inflammation by the PDE4 Inhibitor Roflumilast in Patients With COPD
    Marquez-martin, Eduardo
    Ortega, Francisco
    Campano, Elena
    de la Horra, Carmen
    Varela, Jose
    Calderon, Enrique
    CHEST, 2013, 144 (04)
  • [47] The effect of a single inhaled dose of a VLA-4 antagonist on allergen-induced airway responses and airway inflammation in patients with asthma
    Ravensberg, A. J.
    Luijk, B.
    Westers, P.
    Hiemstra, P. S.
    Sterk, P. J.
    Lammers, J. W.
    Rabe, K. F.
    ALLERGY, 2006, 61 (09) : 1097 - 1103
  • [48] Anti-inflammatory effects of the phosphodiesterase type 4 inhibitor CHF6001 on bronchoalveolar lavage lymphocytes from asthma patients
    Southworth, Thomas
    Kaur, Manminder
    Hodgson, Lynsey
    Facchinetti, Fabrizio
    Villetti, Gino
    Civelli, Maurizio
    Singh, Dave
    CYTOKINE, 2019, 113 : 68 - 73
  • [49] Anti-inflammatory effects of the novel phosphodiesterase type 4 inhibitor CHF6001 on COPD alveolar macrophages and lung tissue
    Lea, Simon
    Metryka, Aleksandra
    Facchinetti, Fabrizio
    Civelli, Maurizio
    Villetti, Gino
    Singh, Dave
    EUROPEAN RESPIRATORY JOURNAL, 2014, 44
  • [50] Pharmacology of SCH900182, a Potent, Selective Inhibitor of PDE4 for Inhaled Administration
    Chapman, R. W.
    House, A.
    Richard, J.
    Fernandez, X.
    Jones, H.
    Prelusky, D.
    Lamca, J.
    Wang, P.
    Lundell, D.
    Ping, W.
    Kuvelkar, R.
    Anthes, J.
    Ting, P. C.
    Lee, J. F.
    Kuang, R.
    Aslanian, R.
    Phillips, J. E.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 181