A novel recombinant human anti-PD-1 monoclonal antibody GLS-010 in patients with advanced cancer: Result of a phase Ia clinical trial

被引：0
|
作者：
Shen, L. [1 ]
Gong, J. [1 ]
Xu, Y. [1 ]
Zhang, X. [1 ]
Peng, Z. [1 ]
Qi, C. [1 ]
Li, G. [2 ]
Meng, H. [2 ]
Liu, Z. [2 ]
Wang, H. [2 ]
Chen, C. [3 ]
Li, J. [3 ]
Zheng, Y. [3 ]
Lee, J. [4 ]
Zhang, Y. [4 ]
Zhang, Q. [4 ]
机构：
[1] Peking Univ, Canc Hosp & Inst, Dept Gastrointestinal Oncol, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing, Peoples R China
[2] Guangzhou Gloria Biosci Co Ltd, Gloria Biosci, Beijing, Peoples R China
[3] WuXi Biol Shanghai Co Ltd, WuXi Biol, Shanghai, Peoples R China
[4] Wuxi Clin Dev Serv Shanghai Co Ltd, Wuxi Clin, Shanghai, Peoples R China
来源：
ANNALS OF ONCOLOGY | 2018年 / 29卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
65P
引用
收藏
页数：2
相关论文
共 50 条
  • [41] The Impact of Liver Metastasis on Anti-PD-1 Monoclonal Antibody Monotherapy in Advanced Melanoma: Analysis of Five Clinical Studies
    Wang, Xuan
    Ji, Qing
    Yan, Xieqiao
    Lian, Bin
    Si, Lu
    Chi, Zhihong
    Sheng, Xinan
    Kong, Yan
    Mao, Lili
    Bai, Xue
    Tang, Bixia
    Li, Siming
    Zhou, Li
    Cui, Chuanliang
    Guo, Jun
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [42] Phase I/Ib Clinical Trial of Sabatolimab, an Anti-TIM-3 Antibody, Alone and in Combination with Spartalizumab, an Anti-PD-1 Antibody, in Advanced Solid Tumors
    Curigliano, Giuseppe
    Gelderblom, Hans
    Mach, Nicolas
    Doi, Toshihiko
    Tai, David
    Forde, Patrick M.
    Sarantopoulos, John
    Bedard, Philippe L.
    Lin, Chia-Chi
    Hodi, F. Stephen
    Wilgenhof, Sofie
    Santoro, Armando
    Sabatos-Peyton, Catherine A.
    Longmire, Tyler A.
    Xyrafas, Alexandros
    Sun, Haiying
    Gutzwiller, Sabine
    Manenti, Luigi
    Naing, Aung
    CLINICAL CANCER RESEARCH, 2021, 27 (13) : 3620 - 3629
  • [43] PHASE 1 TRIAL OF FIRST-IN-CLASS ANTI-CD96 MONOCLONAL ANTIBODY INHIBITOR, GSK6097608, MONOTHERAPY AND COMBINATION WITH ANTI-PD-1 MONOCLONAL ANTIBODY, DOSTARLIMAB, IN ADVANCED SOLID TUMORS
    Hamid, Omid
    Baxter, Dawn
    Easton, Rachael
    Siu, Lilian
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 : A518 - A518
  • [44] Granulomatous and lichenoid dermatitis after IgG4 anti-PD-1 monoclonal antibody therapy for advanced cancer
    Diaz-Perez, Julio A.
    Beveridge, Mara G.
    Victor, Thomas A.
    Cibull, Thomas L.
    JOURNAL OF CUTANEOUS PATHOLOGY, 2018, 45 (06) : 434 - 438
  • [45] Neutrophil/Lymphocyte Ratio Predicts the Efficacy of Anti-PD-1 Antibody in Patients with Advanced Lung Cancer
    Suh, Koung Jin
    Kim, Se Hyun
    Kim, Yu Jung
    Kim, Miso
    Keam, Bhumsuk
    Kim, Tae Min
    Kim, Dong-Wan
    Heo, Dae Seog
    Lee, Jong Seok
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S1312 - S1313
  • [46] Safety and clinical activity with an anti-PD-1 antibody JS']JS001 in advanced melanoma or urologic cancer patients
    Tang, Bixia
    Yan, Xieqiao
    Sheng, Xinan
    Si, Lu
    Cui, Chuanliang
    Kong, Yan
    Mao, Lili
    Lian, Bin
    Bai, Xue
    Wang, Xuan
    Li, Siming
    Zhou, Li
    Yu, Jiayi
    Dai, Jie
    Wang, Kai
    Hu, Jinwei
    Dong, Lihou
    Song, Haifeng
    Wu, Hai
    Feng, Hui
    Yao, Sheng
    Chi, Zhihong
    Guo, Jun
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 12
  • [47] Prognostic Impact of Sarcopenia and Radiotherapy in Patients With Advanced Gastric Cancer Treated With Anti-PD-1 Antibody
    Kim, Nalee
    Yu, Jeong Il
    Lim, Do Hoon
    Lee, Jeeyun
    Kim, Seung Tae
    Hong, Jung Yong
    Kang, Won Ki
    Jeong, Woo Kyoung
    Kim, Kyoung-Mee
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [48] Detailed safety profile of the anti-PD-1 monoclonal antibody pembrolizumab in 78 consecutive patients (pts) with advanced melanoma
    Boutros, C.
    Routier, E.
    Hua, C.
    Texier, M.
    Mateus, C.
    Libenciuc, C.
    Reigneau, M.
    Benannoune, N.
    Roy, S.
    Lanoy, E.
    Le Pavec, J.
    Ladurie, F. L.
    Carbonnel, F.
    Lambotte, O.
    Izzedine, H.
    Berdelou, A.
    Champiat, S.
    Soria, J-C.
    Eggermont, A.
    Robert, C.
    ANNALS OF ONCOLOGY, 2016, 27
  • [49] Eosinophilia predicted longer survival for solid tumor cancer patients treated with anti-PD-1 monoclonal antibody
    Suzuki, Kazuhito
    Nishiwaki, Kaichi
    Miki, Jun
    Takahashi, Naoto
    Odaka, Makoto
    Takagi, Masamichi
    Katori, Mitsuji
    Yano, Shingo
    ANNALS OF ONCOLOGY, 2021, 32 : S350 - S350
  • [50] Recombinant humanized anti-PD-1 monoclonal antibody toripalimab in patients with metastatic urothelial carcinoma: Preliminary results of an open-label phase II clinical study.
    Sheng, Xinan
    Chen, Haige
    Yao, Xin
    Hu, Yi
    Yao, Xudong
    Liu, Ziling
    Zhou, Fangjian
    Huang, Yiran
    Guo, Jun
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
12345