Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

被引：26

作者：

De Boni, Raquel B. ^{[1
]}

Shepherd, Bryan E. ^{[2
]}

Grinsztejn, Beatriz ^{[1
]}

Cesar, Carina ^{[3
]}

Cortes, Claudia ^{[4
]}

Padgett, Denis ^{[6
]}

Gotuzzo, Eduardo ^{[5
]}

Belaunzaran-Zamudio, Pablo F. ^{[7
]}

Rebeiro, Peter F. ^{[2
]}

Duda, Stephany N. ^{[2
]}

McGowan, Catherine C. ^{[2
]}

机构：

[1] Inst Nacl Infectol Evandro Chagas FIOCRUZ, Ave Brasil 4365, BR-21040360 Rio De Janeiro, Brazil

[2] Vanderbilt Univ, 221 Kirkland Hall, Nashville, TN 37235 USA

[3] Fdn Huesped, Buenos Aires, DF, Argentina

[4] Fdn Arriaran, Santiago, Chile

[5] Inst Hondureno Seguridad Social & Hosp Escuela, Tegucigalpa, Honduras

[6] Univ Peruana Cayetano Heredia, Lima, Peru

[7] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Infectol, Mexico City, DF, Mexico

来源：

AIDS AND BEHAVIOR | 2016年 / 20卷 / 11期

关键词：

Substance use; Adherence; HIV/AIDS; Latin America; HIV TREATMENT OUTCOMES; ALCOHOL-USE DISORDERS; ILLICIT DRUG-USE; ANTIRETROVIRAL THERAPY; HEALTH-CARE; COCAINE USE; MEDICATION ADHERENCE; VIRAL SUPPRESSION; INFECTED PEOPLE; BRAZIL;

D O I：

10.1007/s10461-016-1398-6

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having aeyen1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99-3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02-6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19-7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.

引用

页码：2692 / 2699

页数：8

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