Ochronosis: An unusual finding at aortic valve replacement

被引：0
|
作者：
Helou, J [1 ]
Masters, RG [1 ]
Keon, WJ [1 ]
Veinot, JP [1 ]
机构：
[1] Univ Ottawa, Inst Heart, Div Cardiac Surg, Ottawa, ON K1N 6N5, Canada
来源：
CANADIAN JOURNAL OF CARDIOLOGY | 1999年 / 15卷 / 09期
关键词：
aortic valve; calcification; collagen; stenosis; surgery;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The condition known as ochronosis refers to the accumulation of oxidized homogentisic acid in the connective tissues of alkaptonuric patients. The diagnosis is usually made from the triad of degenerative arthritis, ochronotic connective tissue pigmentation and urine chat turns dark brown or black on alkalinization. Cardiovascular disease is a less well appreciated aspect of this disorder. A patient with ochronosis of his stenotic aortic valve is reported. The role of the pigment in the genesis of the valve degeneration is discussed.
引用
收藏
页码：1013 / 1015
页数：3
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