Lineshape Estimation in In Vivo MR Spectroscopy without using a Reference Signal

被引：0

作者：

Popa, E. ^{[1
]}

Graveron-Demilly, D. ^{[1
]}

Capobianco, E. ^{[2
]}

de Beer, R. ^{[3
]}

van Ormondt, D. ^{[3
]}

机构：

[1] Univ Lyon 1, INSERM, CNRS, CREATIS RMN,UMR 5220,INSA Lyon, F-69622 Villeurbanne, France

[2] CRS4 Bioinformat Lab, Cagliari, Italy

[3] Delft Univ Technol, Dept Appl Phys, Delft, Netherlands

来源：

2008 IEEE INTERNATIONAL WORKSHOP ON IMAGING SYSTEMS AND TECHNIQUES | 2008年

关键词：

metabolomics; MR Spectroscopy; in vivo; asymmetric lineshape; estimation error; simulations;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Metabolites can serve as biomarkers. Estimation of metabolite concentrations from an in vivo MRS signal often uses a reference signal from water for correction of the spectral line-shape. When no reference signal is available, other methods must be applied. The present work concerns semi-parametric estimation of the perturbed line-shape from simulated signals of the metabolites themselves. Errors are obtained from a Monte-Carlo calculation. The method can be useful when the water signal has not been acquired or is distorted, or when measuring on, e.g., C-13 or P-31.

引用

页码：313 / +

页数：3

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