New circulating genomic variant of Crimean-Congo hemorrhagic fever virus in Iran

被引:22
|
作者
Chinikar, Sadegh [1 ]
Shah-Hosseini, Nariman [1 ]
Bouzari, Saeid [2 ]
Jalali, Tahmineh [1 ]
Shokrgozar, Mohammad Ali [3 ]
Mostafavi, Ehsan [4 ]
机构
[1] Pasteur Inst Iran, Natl Ref Lab, Arboviruses & Viral Haemorrhag Fevers Lab, Tehran, Iran
[2] Pasteur Inst Iran, Dept Mol Biol, Tehran, Iran
[3] Pasteur Inst Iran, Natl Cell Bank Iran, Tehran, Iran
[4] Pasteur Inst Iran, Dept Epidemiol, Tehran, Iran
关键词
SURVEILLANCE;
D O I
10.1007/s00705-012-1588-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Crimean-Congo hemorrhagic fever is a viral infection that is caused by Crimean-Congo hemorrhagic fever virus (CCHFV). On May 27, 2012, a woman became ill after accidentally splashing cow's blood into her eyes. Serological and molecular investigations were carried out on the serum of the patient. The test results for serological testing were negative, but RT-PCR was strongly positive for CCHFV. A phylogenetic study on the CCHFV genome sequence showed 50 % similarity to a 520-bp region of Russian strains. By combining historical phylogenetic data and current data, it can be surmised that there are potentially more than five circulating CCHFV genomic variants in Iran.
引用
收藏
页码:1085 / 1088
页数:4
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