Modeling and Targeting MLL-PTD/RUNX1 Related MDS/AML In Mouse

被引:0
|
作者
Zhang, Yue
Yan, Xiaomei
Chen, Aili
Sashida, Goro
Xiao, Zhijian
Huang, Gang
机构
关键词
D O I
10.1182/blood.V122.21.2746.2746
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2746
引用
收藏
页数:2
相关论文
共 50 条
  • [41] A new pathway for the transformation of AML in MDS: APA mechanism regulated by NUDT21 and RUNX1
    Li, Shuo
    Ren, Fanggang
    Liu, Xiao-Li
    Zhang, Hong-Yu
    Xu, Zhi-Fang
    Muyey, Daniel Muteb
    Zheng, Zhuanzhen
    Tan, Yan-Hong
    Chen, Xiu-Hua
    Wang, Hong-Wei
    NEOPLASMA, 2023, 70 (03) : 350 - 360
  • [42] Partial tandem duplication of the MLL-Gene (MLL-PTD): A metaanalysis of 2885 AML patients enrolled into the German AMLCG99 and AML96 SHG trials.
    Schnittger, S
    Thiede, C
    Kern, W
    Steudel, C
    Schoch, C
    Schaich, M
    Haferlach, T
    Wermke, M
    Buechner, T
    Ehninger, G
    Hiddemann, W
    BLOOD, 2003, 102 (11) : 100A - 100A
  • [43] RUNX1 Mutations in Normal Karyotype MDS Cooperate with Class I Mutations in the Progression to S-AML Following MDS
    Dicker, Frank
    Haferlach, Claudia
    Kern, Wolfgang
    Haferlach, Torsten
    Schnittger, Susanne
    BLOOD, 2008, 112 (11) : 342 - 342
  • [44] The ability of MLLto bind RUNX1 and methylate H3K4 at PU. 1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations
    Huang, Gang
    Zhao, Xinghui
    Wang, Lan
    Elf, Shannon
    Xu, Hao
    Zhao, Xinyang
    Sashida, Goro
    Zhang, Yue
    Liu, Yan
    Lee, Jennifer
    Menendez, Silvia
    Yang, Youyang
    Yan, Xiaomei
    Zhang, Pu
    Tenen, Daniel G.
    Osato, Motomi
    Hsieh, James J. -D.
    Nimer, Stephen D.
    BLOOD, 2011, 118 (25) : 6544 - 6552
  • [45] RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development
    Yan, Xiaomei
    Hayashi, Yoshihiro
    Zhao, Xinghui
    Chen, Aili
    Zhang, Yue
    He, Fuhong
    Dong, Yunzhu
    Rao, Yalan
    Li, Bo
    Conway, Rajeana
    Maiques-Diaz, Alba
    Huang, Nuomin
    Elf, Shannon E.
    Zuber, Johannes
    Xiao, Zhijian
    Tse, William
    Tenen, Daniel G.
    Wang, Qianfei
    Chen, Wei
    Mulloy, James C.
    Nimer, Stephen D.
    Huang, Gang
    BLOOD, 2014, 124 (21)
  • [46] Toward personalized therapy in AML: in vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML
    Bernot, K. M.
    Siebenaler, R. F.
    Whitman, S. P.
    Zorko, N. A.
    Marcucci, G. G.
    Santhanam, R.
    Ahmed, E. H.
    Ngangana, M.
    McConnell, K. K.
    Nemer, J. S.
    Brook, D. L.
    Kulp, S. K.
    Chen, C. S.
    Frankhouser, D.
    Yan, P.
    Bundschuh, R.
    Zhang, X.
    Dorrance, A. M.
    Dickerson, K. E.
    Jarjoura, D.
    Blum, W.
    Marcucci, G.
    Caligiuri, M. A.
    LEUKEMIA, 2013, 27 (12) : 2379 - 2382
  • [47] Toward personalized therapy in AML: in vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML
    K M Bernot
    R F Siebenaler
    S P Whitman
    N A Zorko
    G G Marcucci
    R Santhanam
    E H Ahmed
    M Ngangana
    K K McConnell
    J S Nemer
    D L Brook
    S K Kulp
    C S Chen
    D Frankhouser
    P Yan
    R Bundschuh
    X Zhang
    A M Dorrance
    K E Dickerson
    D Jarjoura
    W Blum
    G Marcucci
    M A Caligiuri
    Leukemia, 2013, 27 : 2379 - 2382
  • [48] Runx1/AML1 in Normal and Abnormal Hematopoiesis
    Tetsuya Yamagata
    Kazuhiro Maki
    Kinuko Mitani
    International Journal of Hematology, 2005, 82 : 1 - 8
  • [49] Targeted Therapy for AML Expressing RUNX1 Mutation
    Mill, Christopher Peter
    Fiskus, Warren
    DiNardo, Courtney D.
    Qian, Yimin
    Raina, Kanak
    Takahashi, Koichi
    Kadia, Tapan
    Saenz, Dyana T.
    Nowak, Agnieszka J.
    Sun, Baohua
    Crews, Craig M.
    Bhalla, Kapil N.
    BLOOD, 2017, 130
  • [50] RUNX1/AML1: A Central Player in Hematopoiesis
    Tsukasa Okuda
    Motohiro Nishimura
    Mitsushige Nakao
    Yasuko Fujitaa
    International Journal of Hematology, 2001, 74 : 252 - 257