Loss of renal phosphate wasting in a child with autosomal dominant hypophosphatemic rickets caused by a FGF23 mutation

被引：26

作者：

Kruse, K ^{[1
]}

Woelfel, D ^{[1
]}

Storm, TM ^{[1
]}

机构：

[1] Univ Klinikum Lubeck, Klin Kinder Jugendmed, D-23538 Lubeck, Germany

来源：

HORMONE RESEARCH | 2001年 / 55卷 / 06期

关键词：

autosomal dominant hypophosphatemic rickets; X-linked hypophosphatemic rickets; phosphate-regulating gene; fibroblast growth factor 23; renal phosphate wasting;

D O I：

10.1159/000050018

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A girl with autosomal dominant hypophosphatemic rickets, presented with clinical, radiological and laboratory signs of rickets at the age of 11 months. She showed a good response to the treatment with low doses of oral phosphate and calcitriol. Surprisingly, she lost her renal phosphate wasting at the age of 8 years, indicating that the disturbed phosphate metabolism can be compensated by hormonal or other factors. Copyright (C) 2002 S. Karger AG, Basel.

引用

页码：305 / 308

页数：4

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