Effects of proliferation and apoptosis in human gastric cancer cell line SGC-7901 induced by Zedoary turmeric oil

被引：4
|
作者：
Shao, Shu-Li [1 ]
Sui, Wen-Jing [1 ]
Li, Shuang [1 ]
Zhang, Wei-Wei [1 ]
Zhao, Wei
Song, Jin-Ping [1 ]
机构：
[1] Qiqihar Univ, Coll Life Sci, Qiqihar, Hei Longjiang P, Peoples R China
来源：
ADVANCES IN ENVIRONMENTAL ENGINEERING | 2012年 / 599卷
关键词：
Zedoary turmeric oil; gastric cancer; SGC-7901; apoptosis; CURCUMIN;
D O I：
10.4028/www.scientific.net/AMR.599.67
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Objective To study the effect of Zedoary turmeric oil on proliferation and apoptosis of human gastric cancer cell line SGC-7901. The growth inhibition rate of different concentration of Zedoary turmeric oil on human gastric cancer cell line SGC-7901 were detected by trypan blue stain assay. Optical microscopy observation of cell morphological changes. DNA fragmentation detected by agarose gel electrophoresis. Flow cytometry was used to detect the changes of cell mitochondrial membrane potential, apoptosis rate and cell cycle distribution. Results: the optimal concentration was110 mu g/mL for 48h, and the IC50 values were 104.958 mu g/mL. The typical DNA ladder on agarose gel electrophoresis, the apoptotic peak was showed by FCA detection. Conclusion: The Zedoary turmeric oil can induce apoptosis of gastric cancer cell SGC-7901.
引用
收藏
页码：67 / 70
页数：4
相关论文
共 50 条
  • [1] Apoptosis of Human Gastric Cancer Cell Line SGC-7901 Induced by Allicin
    Shao Shu-Li
    Zhang Wei-Wei
    Li Feng-Ying
    MATERIALS FOR ENVIRONMENTAL PROTECTION AND ENERGY APPLICATION, PTS 1 AND 2, 2012, 343-344 : 1285 - 1289
  • [2] Apoptosis induced by GanoPoly in human gastric cancer cell line SGC-7901 cells
    Hui, Tao Wen
    Hong, Liu
    Gang, Li
    Qing, Zhu You
    Rui, Qin
    AFRICAN JOURNAL OF BIOTECHNOLOGY, 2011, 10 (79): : 18279 - 18284
  • [3] Effect of ADM on proliferation and apoptosis of human gastric cancer cell SGC-7901
    Shao, ShuLi
    Chen, WeiWei
    Zhang, WeiWei
    Zhao, Wei
    Li, FengYing
    ADVANCED ENGINEERING MATERIALS II, PTS 1-3, 2012, 535-537 : 2434 - 2437
  • [4] Effects of ophiopogonin B on the proliferation and apoptosis of SGC-7901 human gastric cancer cells
    Zhang, Weiyue
    Zhang, Qiaoyan
    Jiang, Yiping
    Li, Feng
    Xin, Hailiang
    MOLECULAR MEDICINE REPORTS, 2016, 13 (06) : 4981 - 4986
  • [5] Effects of mifepristone on proliferation of human gastric adenocarcinoma cell line SGC-7901 in vitro
    Li, Da-Qiang
    Wang, Zhi-Biao
    Bai, Jin
    Zhao, Jie
    Wang, Yuan
    Hu, Kai
    Du, Yong-Hong
    WORLD JOURNAL OF GASTROENTEROLOGY, 2004, 10 (18) : 2628 - 2631
  • [6] Effects of sufentanil on human gastric cancer cell line SGC-7901 in vitro
    Wu, Weidong
    Wei, Ningxian
    Jiang, Chun-Nan
    Cui, Suyang
    Yuan, Jintao
    CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY, 2014, 39 (03) : 299 - 305
  • [7] Effects of mifepristone on proliferation of human gastric adenocarcinoma cell line SGC-7901 in vitro
    Da-Qiang Li Zhi-Biao Wang Jin Bai Jie Zhao Yuan Wang Kai Hu Yong-Hong Du State Key Laboratory of Ultrasound Engineering in Medicine
    World Journal of Gastroenterology, 2004, (18) : 2628 - 2631
  • [8] Apoptosis of human gastric cancer SGC-7901 cells induced by podophyllotoxin
    Ji, Chen-Feng
    Ji, Yu-Bin
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2014, 7 (05) : 1317 - 1322
  • [9] Effect of Evodiamine on Inducing Apoptosis of Human Gastric Cancer Cell Line SGC-7901 in Vitro
    Liu Shao-Ping
    Qian Wen-Jun
    Mao Wei-Dong
    JOURNAL OF INTERNATIONAL TRANSLATIONAL MEDICINE, 2014, 2 (03): : 380 - 384
  • [10] Regulation of apoptosis in human gastric cancer cell line SGC-7901 by L-arginine
    Shu, X. L.
    Xu, H.
    Yu, T. T.
    Zhong, J. X.
    Lei, T.
    PANMINERVA MEDICA, 2014, 56 (03) : 227 - 231
12345