Development and characterization of evening primrose (Oenothera biennis) oil nanoemulsions

被引：35
|
作者：
Rodrigues, Railane F. [1 ]
Costa, Isabele C. [1 ]
Almeida, Fernanda B. [1 ]
Cruz, Rodrigo A. S. [1 ]
Ferreira, Adriana M. [2 ]
Vilhena, Jessica C. E.
Florentino, Alexandro C. [3 ]
Carvalho, Jose C. T. [2 ]
Fernandes, Caio P. [1 ]
机构：
[1] Univ Fed Amapa, Curso Farm, Lab Nanobiotecnol Fitofarmaceut, Macapa, AP, Brazil
[2] Univ Fed Amapa, Curso Farm, Lab Pesquisa Farmacos, Macapa, AP, Brazil
[3] Univ Fed Amapa, Curso Farm, Lab Absorcao Atom & Bioprospeccao, Macapa, AP, Brazil
来源：
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY | 2015年 / 25卷 / 04期
关键词：
Evening primrose; Nanoemulsion; Oenothera biennis; STABILITY; EMULSIONS; SEEDS; L;
D O I：
10.1016/j.bjp.2015.07.014
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Evening primrose (Oenothera biennis L., Onagraceae) seeds oil has great economic importance due to its wide industrial application, mainly for medicines and nutraceutics. However, to our knowledge, it remains almost unexplored regarding development of innovative formulations, such as nanoemulsions. On the present study, required HydroprophileLipophile Balance of evening primrose seeds oil was determined (HLB 12) and a stable nanoemulsion (Day 1: mean droplet size: 214.3 +/- 0.69 nm, polydispersity index: 0.253 +/- 0.012. Day 7: mean droplet size: 202.8 +/- 0.23 nm, polydispersity index: 0.231 +/- 0.008) was achieved. Moreover, pseudo-ternary diagram allowed delimitation of nanoemulsion region, contributing to nanobiotechnology of natural products. (C) 2015 Sociedade Brasileira de Farmacognosia. Published by Elsevier Editora Ltda. All rights reserved.
引用
收藏
页码：422 / 425
页数：4
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