Potential role of statins in COVID-19

被引:70
|
作者
Lee, Ken Cheah Hooi [1 ]
Sewa, Duu Wen [1 ]
Phua, Ghee Chee [1 ]
机构
[1] Singapore Gen Hosp, Dept Resp & Crit Care Med, Singapore, Singapore
关键词
RANDOMIZED-TRIAL; INFLUENZA; THERAPY; RISK;
D O I
10.1016/j.ijid.2020.05.115
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Patients with COVID-19 infection have an increased risk of cardiovascular complications and thrombotic events. Statins are known for their pleiotropic anti-inflammatory, antithrombotic and immunomodulatory effects. They may have a potential role as adjunctive therapy to mitigate endothelial dysfunction and dysregulated inflammation in patients with COVID-19 infection. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
引用
收藏
页码:615 / 617
页数:3
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