Two Vanadium Oxide Metal Coordination Complexes: Inhibiting Growth of Human Gastric Cancer Cells

被引：0
|
作者：
Zhong, Wane [1 ]
Cao, Ping [1 ]
Zhou, Guoxiong [2 ]
机构：
[1] Ningbo Sixth Hosp, Dept Gastroenterol, Ningbo, Zhejiang, Peoples R China
[2] Nantong Univ, Dept Gastroenterol, Affiliated Hosp, Nantong, Jiangsu, Peoples R China
来源：
LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 01期
关键词：
anticancer activity; coordination complex; single-crystal; HYDRAZONE LIGANDS;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Two new vanadium oxide metal coordination complexes [Zn(phen)(H2O)V2O6] (1) and Co(bipy)(H2O)V2O6 (2) have been isolated by hydrothermal method. Single-crystal X-ray diffraction analysis reveals that 1 consists of one-dimensional chains built up from covalently linked [V4O12](4-) rings and [Zn(phen)(H2O)](2+) fragments; 2 exhibits a 2D network structure, constructed by vanadium oxide chain {V2O6}(2n-)n and covalently linked by Co(bipy)(H2O)(2+) subunits. In addition, in vitro anticancer activity of the title compounds 1 and 2 on three human gastric cancer line cells (SGC7901, MKN45 and BGC-823) was further determined.
引用
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页码：12 / 15
页数：4
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