Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital

被引:2
|
作者
Saavedra, Pamela Alejandra [1 ]
Milward de Azevedo Meiners, Micheline Marie [2 ]
Lopes, Luciane Cruz [3 ]
da Silva, Emilia Vitria [2 ]
Mendonca da Silva, Dayde Lane [1 ]
Noronha, Elza Ferreira [4 ]
de Toledo, Maria Ines [1 ]
机构
[1] Univ Brasilia, Fac Ciencias Saude, Ceilandia, DF, Brazil
[2] Univ Brasilia, Fac Ceilandia, Ceilandia, DF, Brazil
[3] Univ Sorocaba, Programa Posgrad Ciencias Farmaceut, Sorocaba, SP, Brazil
[4] Univ Brasilia, Fac Med, Nucleo Med Trop, Brasilia, DF, Brazil
关键词
Adverse drug reactions; Pharmacovigilance; Hospitals; EVENTS;
D O I
10.1590/0037-8682-0238-2016
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Introduction: Despite the therapeutic benefits of drugs, adverse drug reactions (ADRs) occur. Method: We assessed a series of suspected ADRs identified from notifications and intensive monitoring of inpatients from March 2013 to March 2014. Results: Skin reactions predominated (31%). Systemic anti-infective agents were implicated in 16 (72%) reactions. Fifteen (68%) ADRs were classified as possible. The implicated drug was not correctly identified by the healthcare team in 12 cases. Conclusions: Some reactions were not correctly attributed to the causative drug(s), suggesting that the use of a validated evaluation method can promote successful identification of causal links between ADRs and drugs.
引用
收藏
页码:763 / 767
页数:5
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