Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital

被引:2
|
作者
Saavedra, Pamela Alejandra [1 ]
Milward de Azevedo Meiners, Micheline Marie [2 ]
Lopes, Luciane Cruz [3 ]
da Silva, Emilia Vitria [2 ]
Mendonca da Silva, Dayde Lane [1 ]
Noronha, Elza Ferreira [4 ]
de Toledo, Maria Ines [1 ]
机构
[1] Univ Brasilia, Fac Ciencias Saude, Ceilandia, DF, Brazil
[2] Univ Brasilia, Fac Ceilandia, Ceilandia, DF, Brazil
[3] Univ Sorocaba, Programa Posgrad Ciencias Farmaceut, Sorocaba, SP, Brazil
[4] Univ Brasilia, Fac Med, Nucleo Med Trop, Brasilia, DF, Brazil
关键词
Adverse drug reactions; Pharmacovigilance; Hospitals; EVENTS;
D O I
10.1590/0037-8682-0238-2016
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Introduction: Despite the therapeutic benefits of drugs, adverse drug reactions (ADRs) occur. Method: We assessed a series of suspected ADRs identified from notifications and intensive monitoring of inpatients from March 2013 to March 2014. Results: Skin reactions predominated (31%). Systemic anti-infective agents were implicated in 16 (72%) reactions. Fifteen (68%) ADRs were classified as possible. The implicated drug was not correctly identified by the healthcare team in 12 cases. Conclusions: Some reactions were not correctly attributed to the causative drug(s), suggesting that the use of a validated evaluation method can promote successful identification of causal links between ADRs and drugs.
引用
收藏
页码:763 / 767
页数:5
相关论文
共 50 条
  • [1] Pattern of Adverse Drug Reactions (adrs) Among Patients Admitted in a Tertiary Care Teaching Hospital
    Raja, Sangeetha
    Rani, Jamuna R.
    INDIAN JOURNAL OF PHARMACOLOGY, 2013, 45 : S43 - S44
  • [2] Adverse drug reactions in patients in the department of Infectious diseases in Sfax, Tunisia
    Ben Mahmoud, L.
    Ghozzi, H.
    Hammami, B.
    Hakim, A.
    Sahnoun, Z.
    Hammami, S.
    Athaymen, R.
    Affes, H.
    Benjmaa, M.
    Zeghal, K. H.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2010, 24 : 70 - 70
  • [3] Prevalence and risk factors associated with fatal adverse drug reactions among patients admitted at a Spanish teaching hospital
    Jose Pardo-Cabello, Alfredo
    de Dios Luna, Juan
    Gomez Jimenez, Francisco Javier
    Del Pozo, Esperanza
    Puche Canas, Emilio
    EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2019, 70 : E14 - E16
  • [4] Detection and Prevention of Adverse Drug Reactions in In-Patients of a Brazilian University Hospital
    C. A. Takagi
    M. C. S. Ricci
    M. C. Sakai
    G. G. França
    S. C. Brassica
    A. M. Yamaguchi
    C. P. Rodrigues
    E. Ribeiro
    Drug Safety, 2008, 31 : 885 - 885
  • [5] Adverse drug reactions in hospitalized children in a department of infectious diseases
    Fattahi, F
    Pourpak, Z
    Moin, M
    Kazemnejad, A
    Khotoei, GT
    Mamishi, S
    Siadati, A
    Tabatabaei, P
    JOURNAL OF CLINICAL PHARMACOLOGY, 2005, 45 (11): : 1313 - 1318
  • [6] Detection and Prevention of Adverse Drug Reactions in In-Patients of a Brazilian University Hospital.
    Takagi, C. A.
    Ricci, M. C. S.
    Sakai, M. C.
    Franca, G. G.
    Brassica, S. C.
    Yamaguchi, A. M.
    Rodrigues, C. P.
    Ribeiro, E.
    DRUG SAFETY, 2008, 31 (10) : 939 - 939
  • [7] Adverse drug reactions in patients admitted on Internal Medicine wards in a district and Regional Hospital in Uganda
    Tumwikirize, W. A.
    Ogwal-Okeng, J. W.
    Vernby, A.
    Anokbonggo, W. W.
    Gustafsson, L. L.
    Lundborg, S. C.
    AFRICAN HEALTH SCIENCES, 2011, 11 (01) : 72 - 78
  • [8] Evaluation of Adverse Drug Reactions Among In-Patients Admitted into the Adult Medical Wards of University of Ilorin Teaching Hospital, Nigeria
    Ayetoro, S. O.
    Olagunju, A. O.
    Laiyemo, K. A.
    DRUG SAFETY, 2014, 37 (10) : 841 - 842
  • [9] Adverse Drug Reactions in an Ageing PopulaTion rIsk Prediction Tool (ADAPtIP): The development of a Model for Predicting Adverse Drug reactions in older patients Admitted to Hospital
    Frydenlund, Juliane
    Cosgrave, Nicole
    Moriarty, Frank
    Kirke, Ciara
    Williams, David J.
    Bennett, Kathleen E.
    Cahir, Caitriona
    Wallace, Emma
    PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2024, 33 : 377 - 377
  • [10] Polypharmacy among patients admitted to hospital with rheumatic diseases
    Kirsten K. Viktil
    Merethe Enstad
    Janne Kutschera
    Liv Marit Smedstad
    Jan Schjott
    Pharmacy World and Science, 2001, 23 : 153 - 158