Enhancer of Zeste Homolog 2 (EZH2) is a molecular switch in HDAC3-mediated glucolipotoxicity in beta cells

被引:0
|
作者
Dahlby, T. [1 ]
Backe, M. B. [1 ]
Dahllf, M. S. [1 ]
Simon, C. [2 ]
Holson, E. [3 ]
Wagner, B. [3 ]
Lundh, M. [2 ]
Mandrup-Poulsen, T. [1 ]
机构
[1] Univ Copenhagen, Dept Biomed Sci, DK-1168 Copenhagen, Denmark
[2] Univ Copenhagen, DK-1168 Copenhagen, Denmark
[3] Broad Inst, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
471
引用
收藏
页码:S233 / S233
页数:1
相关论文
共 50 条
  • [31] Enhancer of Zeste Homolog 2 (EZH2) in COVID-19-Positive Acute Myeloid Leukemia
    Hamed, Nahla
    Gallab, Omar
    Abdelhalim, Reham
    Rezk, Mohamed
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 : S289 - S290
  • [32] Effects of Enhancer of Zeste Homolog 2 (EZH2) Expression on Brain Glioma Cell Proliferation and Tumorigenesis
    Cheng, Tianci
    Xu, Yinghui
    MEDICAL SCIENCE MONITOR, 2018, 24 : 7249 - 7255
  • [33] Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
    Wagener, Nina
    Macher-Goeppinger, Stephan
    Pritsch, Maria
    Huesing, Johannes
    Hoppe-Seyler, Karin
    Schirmacher, Peter
    Pfitzenmaier, Jesco
    Haferkamp, Axel
    Hoppe-Seyler, Felix
    Hohenfellner, Markus
    BMC CANCER, 2010, 10
  • [34] The role of methyltransferase, enhancer of zeste homolog 2 (EZH2) in mouse hepatocyte and human hepatocellular carcinoma
    Bae, Woo Kyun
    Shim, Hyun Jeong
    Cho, Sang Hee
    Chung, Ik-Joo
    Park, In-Kyu
    Hennighausen, Lothar
    CANCER RESEARCH, 2015, 75
  • [35] Immunohistochemical loss of enhancer of Zeste Homolog 2 (EZH2) protein expression correlates with EZH2 alterations and portends a worse outcome in myelodysplastic syndromes
    Sakhdari, Ali
    Class, Caleb
    Montalban-Bravo, Guillermo
    Sasaki, Koji
    Bueso-Ramos, Carlos E.
    Patel, Keyur P.
    Routbort, Mark J.
    Loghavi, Sanam
    Ok, Chi Young
    Quesada, Andres
    Khoury, Joseph D.
    Konoplev, Sergej N.
    Kantarjian, Hagop P.
    Garcia-Manero, Guillermo
    Medeiros, L. Jeffrey
    Kanagal-Shamanna, Rashmi
    MODERN PATHOLOGY, 2022, 35 (09) : 1212 - 1219
  • [36] Enhancer of zeste homolog 2 (EZH2) gene inhibition via 3-Deazaneplanocin A (DZNep) in human liver cells and it is relation with fibrosis
    Ozel, Merve
    Guven, Ilker
    Kilic, Eser
    Dundar, Munis
    Baskol, Gulden
    TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, 2020, 45 (06): : 737 - 745
  • [37] The enhancer of zeste homolog 2 (EZH2), a potential therapeutic target, is regulated by miR-101 in renal cancer cells
    Sakurai, Toshihiko
    Bilim, Vladimir N.
    Ugolkov, Andrey V.
    Yuuki, Kaori
    Tsukigi, Masaaki
    Motoyama, Teiichi
    Tomita, Yoshihiko
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 422 (04) : 607 - 614
  • [38] Enhancer of zeste homolog 2 (EZH2) regulates tumor angiogenesis and predicts recurrence and prognosis of intrahepatic cholangiocarcinoma
    Nakagawa, Shigeki
    Okabe, Hirohisa
    Ouchi, Mayuko
    Tokunaga, Ryuma
    Umezaki, Naoki
    Higashi, Takaaki
    Kaida, Takatoshi
    Arima, Kota
    Kitano, Yuki
    Kuroki, Hideyuki
    Mima, Kosuke
    Nitta, Hidetoshi
    Imai, Katsunori
    Hashimoto, Daisuke
    Yamashita, Yo-ichi
    Chikamoto, Akira
    Baba, Hideo
    HPB, 2018, 20 (10) : 939 - 948
  • [39] Enhancer zeste homolog 2 (EZH2) targeting by small interfering RNA (siRNA); recent advances and prospect
    Hsu, Chou-Yi
    Mohammed, Abdulsalam Najm
    Hjazi, Ahmed
    Uthirapathy, Subasini
    Renuka, Jyothi S.
    Singh, Abhayveer
    Thyagarajan, Subhashree
    Ray, Subhashree
    Hulail, Hanen Mahmod
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2025,
  • [40] A Novel Mutation Pattern of Enhancer of Zeste Homolog 2(EZH2) in Myelodysplasia-Related Myeloid Neoplasms
    Zhou, Jun
    Nguyen, Johnny
    Zhang, Ling
    MODERN PATHOLOGY, 2015, 28 : 391A - 391A