Enhancer of Zeste Homolog 2 (EZH2) is a molecular switch in HDAC3-mediated glucolipotoxicity in beta cells

被引:0
|
作者
Dahlby, T. [1 ]
Backe, M. B. [1 ]
Dahllf, M. S. [1 ]
Simon, C. [2 ]
Holson, E. [3 ]
Wagner, B. [3 ]
Lundh, M. [2 ]
Mandrup-Poulsen, T. [1 ]
机构
[1] Univ Copenhagen, Dept Biomed Sci, DK-1168 Copenhagen, Denmark
[2] Univ Copenhagen, DK-1168 Copenhagen, Denmark
[3] Broad Inst, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
471
引用
收藏
页码:S233 / S233
页数:1
相关论文
共 50 条
  • [1] Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in β-Cells
    Dahlby, Tina
    Simon, Christian
    Backe, Marie Balslev
    Dahllof, Mattias Sailing
    Holson, Edward
    Wagner, Bridget K.
    Boni-Schnetzler, Marianne
    Marzec, Michal Tomasz
    Lundh, Morten
    Mandrup-Poulsen, Thomas
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (21) : 1 - 18
  • [2] Enhancer of zeste homolog 2 (EZH2) inhibitors
    Gulati, Nitya
    Beguelin, Wendy
    Giulino-Roth, Lisa
    LEUKEMIA & LYMPHOMA, 2018, 59 (07) : 1574 - 1585
  • [3] Enhancer of zeste homolog 2 (EZH2) expression in bladder cancer
    Warrick, Joshua I.
    Raman, Jay D.
    Kaag, Matthew
    Bruggeman, Trey
    Cates, Justin
    Clark, Peter
    DeGraff, David J.
    UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2016, 34 (06) : 258.e1 - 258.e6
  • [4] Epigenetic Control of Osteoblast Differentiation by Enhancer of Zeste Homolog 2 (EZH2)
    Amel Dudakovic
    Andre J. van Wijnen
    Current Molecular Biology Reports, 2017, 3 (2) : 94 - 106
  • [5] Enhancer of Zeste Homolog 2 (EZH2) in Malignant Progression of Gallbladder Carcinoma
    Gayatri Behera
    Suvradeep Mitra
    Tushar S Mishra
    Suvendu Purkait
    Journal of Gastrointestinal Cancer, 2021, 52 : 1029 - 1034
  • [6] Conformationally constrained potent inhibitors for enhancer of zeste homolog 2 (EZH2)
    Xu, Xin
    Chen, Jia
    Wang, Guan
    Zhang, Xiaojuan
    Li, Qiang
    Zhou, Xiaobo
    Guo, Fengying
    Li, Min
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 97
  • [7] Enhancer of Zeste Homolog 2 (EZH2) in Malignant Progression of Gallbladder Carcinoma
    Behera, Gayatri
    Mitra, Suvradeep
    Mishra, Tushar S.
    Purkait, Suvendu
    JOURNAL OF GASTROINTESTINAL CANCER, 2021, 52 (03) : 1029 - 1034
  • [8] Expression of Enhancer of Zeste Homolog 2 (EZH2) in Invasive Neuroendocrine Carcinoma of the Breast
    Gong, Y.
    Chen, J.
    Wang, J.
    Radvanyi, L.
    Rosen, D. G.
    Wu, Y.
    MODERN PATHOLOGY, 2013, 26 : 44A - 45A
  • [9] Value of Enhancer of Zeste Homolog 2 (EZH2) for Determining Prognosis in Colon Cancer
    Gholami, Nassrin
    Sanaat, Zohreh
    Dolatkhah, Roya
    Nikanfar, Alireza
    Esfahani, Ali
    Danandehmehr, Amin
    Akhrjou, Ashraf
    Farassati, Faris
    JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2020, 14 (03)
  • [10] Expression of Enhancer of Zeste Homolog 2 (EZH2) in Invasive Neuroendocrine Carcinoma of the Breast
    Gong, Y.
    Chen, J.
    Wang, J.
    Radvanyi, L.
    Rosen, D. G.
    Wu, Y.
    LABORATORY INVESTIGATION, 2013, 93 : 44A - 45A